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February 01, 1982; 32 (2) Articles

Significance of cortical disinhibition signs

James Tweedy, Michael Reding, Carlos Garcia, Peter Schulman, Georg Deutsch, Sanford Antin
First published February 1, 1982, DOI: https://doi.org/10.1212/WNL.32.2.169
James Tweedy
Ph.D.
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Michael Reding
M.D.
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Carlos Garcia
M.D.
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Peter Schulman
Ph.D.
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Georg Deutsch
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Sanford Antin
M.D.
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Citation
Significance of cortical disinhibition signs
James Tweedy, Michael Reding, Carlos Garcia, Peter Schulman, Georg Deutsch, Sanford Antin
Neurology Feb 1982, 32 (2) 169; DOI: 10.1212/WNL.32.2.169

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Abstract

Several clinical signs traditionally associated with dementia were examined in a series of 103 patients referred to a dementia clinic. The snout and grasp reflexes were significantly correlated with impaired performance on cognitive tests, but not accentuated jaw-jerk, glabellar reflex, paratonia, suck, root, or palmomental reflexes. In general, the signs were more strongly correlated with CT evidence of ventricular dilation than with cortical atrophy. They seem to be related to supranuclear motor system dysfunction, and cannot be considered clinical markers of dementia.

  • © 1982 by the American Academy of Neurology

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