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August 01, 1996; 47 (2) ARTICLES

Headache in ambulatory HIV-1-infected men enrolled in a longitudinal study

Elyse J. Singer, Julie Kim, Bridget Fahy-Chandon, Ashwin Datt, Wallace W. Tourtellotte
First published August 1, 1996, DOI: https://doi.org/10.1212/WNL.47.2.487
Elyse J. Singer
MD
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Julie Kim
BS
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Bridget Fahy-Chandon
BS
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Ashwin Datt
BS
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Wallace W. Tourtellotte
MD, PhD
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Citation
Headache in ambulatory HIV-1-infected men enrolled in a longitudinal study
Elyse J. Singer, Julie Kim, Bridget Fahy-Chandon, Ashwin Datt, Wallace W. Tourtellotte
Neurology Aug 1996, 47 (2) 487-494; DOI: 10.1212/WNL.47.2.487

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Abstract

Objective: To report headache (HA) data collected from subjects in a longitudinal study of human immunodeficiency virus (HIV)-1 and the central nervous system (CNS). Design/methods: Baseline data from 229 ambulatory HIV-seropositive (HIV+) and 53 seronegative control subjects were analyzed. Subjects were classified by the presence or absence of HIV-1-associated HAs and HIV-1-associated systemic and neurologic disease. Subjects were followed longitudinally for up to 5 years. Results: In the cross-sectional analysis, significant associations were observed between HIV-1-associated HAs and (1) anxiety and depression, and (2) a history of drug use, psychiatric disease, and non-HIV-1 neurologic disease. No significant differences in laboratory values were found between subjects with HIV-1-associated HA compared with those without HA. When HIV+ subjects were followed longitudinally, onset of new HIV-1-associated systemic or neurologic disease over 1 year was not predicted by the presence of an HIV-1-associated HA at baseline. Conclusion: Headaches are common in HIV+ persons at all stages of disease. Presence of HIV-1-associated HAs at baseline were not associated with neurologic disease progression over 1 year of follow-up in our sample.

NEUROLOGY 1996;47: 487-494

  • Copyright 1996 by Advanstar Communications Inc.
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