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December 01, 1996; 47 (6) Clinical Scientific Notes

Pseudotumor cerebri and cerebral venous hypertension

Phillip D. Cremer, Elizabeth O. Thompson, Ian H. Johnston, G. Michael Halmagyi
First published December 1, 1996, DOI: https://doi.org/10.1212/WNL.47.6.1602
Phillip D. Cremer
MB, BS, BSc(Med), FRACP
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Elizabeth O. Thompson
MB, BS, FRACR
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Ian H. Johnston
MB, ChB, PhD, FRACS
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G. Michael Halmagyi
MD, FRACP
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Citation
Pseudotumor cerebri and cerebral venous hypertension
Phillip D. Cremer, Elizabeth O. Thompson, Ian H. Johnston, G. Michael Halmagyi
Neurology Dec 1996, 47 (6) 1602-1603; DOI: 10.1212/WNL.47.6.1602

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Pseudotumor cerebri is a syndrome of raised CSF pressure, normal CSF composition, and a normal cerebral CT or MRI. [1] Two recent articles [2,3] emphasized the importance of cerebral venous hypertension in the pathogenesis of pseudotumor cerebri and highlighted the usefulness of cerebral venography and direct pressure measurements in the understanding of this condition. Karahalios et al. [3] postulated that cerebral venous hypertension causes impaired reabsorption of CSF across the arachnoid villi, leading to elevated CSF pressure. We report the case of a woman with pseudotumor cerebri in whom the pathogenesis and correct management could only be formulated after cerebral venography and manometry.

Case report.

A 40-year-old woman presented with asymptomatic papilledema that was detected by an optometrist who was supplying her with new spectacle frames. She had never complained of headache or visual obscurations. Her past medical history included mild asthma (treated with salbutamol, ipratropium bromide, and beclomethasone aerosols) and ulcerative colitis that was well controlled for 11 years on sulphasalazine. She had also been taking hormone replacement therapy for three months before diagnosis, for the symptom …

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