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August 01, 1997; 49 (2) Clinical/Scientific Notes

Perimesencephalic nonaneurysmal subarachnoid hemorrhage: First hint of a cause?

Eelco F.M. Wijdicks, Wouter I. Schievink
First published August 1, 1997, DOI: https://doi.org/10.1212/WNL.49.2.634
Eelco F.M. Wijdicks
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Wouter I. Schievink
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Perimesencephalic nonaneurysmal subarachnoid hemorrhage: First hint of a cause?
Eelco F.M. Wijdicks, Wouter I. Schievink
Neurology Aug 1997, 49 (2) 634-636; DOI: 10.1212/WNL.49.2.634

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A vascular lesion cannot be established by angiography in approximately 15% of patients with a spontaneous subarachnoid hemorrhage.1 Within this subset of patients with a negative cerebral angiogram, 50 to 75% of the initial CTs depict a so-called perimesencephalic pattern.1-3 Typically, there is a propensity of blood to layer around the brain stem, with minimal extension into the fissures and no intraventricular entry.2,3 This pattern has been recognized as a benign variant of nonaneurysmal subarachnoid hemorrhage because none of the patients have rebled or developed cerebral infarction, and long-term outcome is excellent. The cause of perimesencephalic nonaneurysmal hemorrhage has been a mystery. Surgical explorations in a few patients have been unsuccessful in localizing a vascular lesion, and none of the patients has come to autopsy.4,5 We recently had the opportunity to study a patient with a perimesencephalic nonaneurysmal hemorrhage with detailed MR imaging and could demonstrate the presence of a pontine vascular anomaly that most likely represents a capillary telangiectasia.

Case report. A 45-year-old man developed an occipital headache and neck pain while shoveling gravel. The headache came on within 15 seconds and was not associated with loss of consciousness or transient neurologic …

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