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Reply from the Authors: Dr. De Keyser questioned the outcome measurements used in the studies to prepare the practice advisory published in the September, 1996 issues of Neurology.1 The NINDS study,2 for example, defined disability as a Rankin score ≤2 whereas ECASS3 defined it as ≤3. Also, the Barthel index was used in measuring outcome in the NINDS study. As De Keyser notes, "there is no ideal way" to choose outcome measures and the method of dividing outcome scores in the NINDS trial …
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