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Abstract
MS-associated retrovirus (MSRV) in the CSF may have gliotoxic properties and could be associated with a more disabling MS. The authors tested this hypothesis in 15 untreated patients with MS: 6 MSRV− and 9 MSRV+ at the time of CSF withdrawal. After a 3-year mean follow-up, MSRV− patients showed a stable MS course, whereas MSRV+ patients had a progressive course (p = 0.01).
- Received February 8, 2002.
- Accepted June 20, 2002.
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