This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Medullary streaks are linear structures on MRI crossing the white matter of the brain, which can be observed in aging brain or patients with moyamoya disease.1 The increases in medullary streak diameter that accompany advancing age coincide with, and are thought to represent, age-related enlargement of fluid-filled perivascular spaces that have been shown by histology to accompany senile brain atrophy.2 On the other hand, medullary streaks in moyamoya disease are speculatively considered to represent compensatorily dilated medullary vessels rather than the perivascular spaces.1 In this report, we demonstrate contrast enhancement of the medullary streaks in two patients with severe chronic cerebral ischemia (advanced moyamoya disease and progeria syndrome), which supports this hypothesis. We also propose that the medullary streaks and the ivy sign (leptomeningeal enhancement on postcontrast T1-weighted images or hyperintensity on fluid-attenuated inversion recovery [FLAIR] images)3 in ischemic …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Topics Discussed
Alert Me
Recommended articles
Cerebrovascular Disease Progression in Patients With ACTA2 Arg179 Pathogenic Variants
Intracranial arterial wall imaging using high-resolution 3-tesla contrast-enhanced MRI
Carotid intimal sarcoma causing stroke and intracranial metastasis via tumor embolization
Submandibular TCD approach detects post-bulb ICA stenosis in children with sickle cell anemia