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December 28, 2004; 63 (12) Brief Communications

Physical training and fatigue, fitness, and quality of life in Guillain–Barré syndrome and CIDP

M. P.J. Garssen, J. B.J. Bussmann, P. I.M. Schmitz, A. Zandbergen, T. G. Welter, I. S.J. Merkies, H. J. Stam, P. A. van Doorn
First published December 28, 2004, DOI: https://doi.org/10.1212/01.WNL.0000148589.87107.9C
M. P.J. Garssen
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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J. B.J. Bussmann
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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P. I.M. Schmitz
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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A. Zandbergen
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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T. G. Welter
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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I. S.J. Merkies
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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H. J. Stam
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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P. A. van Doorn
From the Departments of Neurology (Drs. Garssen and van Doorn), Rehabilitation (Drs. Bussmann and Stam, A. Zandbergen), and Statistics (Dr. Schmitz), Erasmus Medical Center Rotterdam, and Department of Neurology (Dr. Merkies), Spaarne Hospital, Haarlem, the Netherlands.
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Full PDF
Citation
Physical training and fatigue, fitness, and quality of life in Guillain–Barré syndrome and CIDP
M. P.J. Garssen, J. B.J. Bussmann, P. I.M. Schmitz, A. Zandbergen, T. G. Welter, I. S.J. Merkies, H. J. Stam, P. A. van Doorn
Neurology Dec 2004, 63 (12) 2393-2395; DOI: 10.1212/01.WNL.0000148589.87107.9C

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Abstract

Many patients with Guillain–Barré syndrome (GBS) and chronic inflammatory demyelinating polyneuropathy (CIDP) experience excessive fatigue, which may persist for years and reduce quality of life. The authors performed a 12-week study of bicycle exercise training in 20 patients with severe fatigue, 16 with relatively good recovery from GBS, and 4 with stable CIDP. Training seemed well tolerated, and self-reported fatigue scores decreased 20% (p = 0.001). Physical fitness, functional outcome, and quality of life were improved.

  • Received May 21, 2004.
  • Accepted in final form August 12, 2004.
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