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February 22, 2005; 64 (4) Clinical/Scientific Notes

Spinal cord transient ischemic attacks: A possible role for abciximab

Muhammad S. Hussain, Ashfaq Shuaib, Zaeem A. Siddiqi
First published February 22, 2005, DOI: https://doi.org/10.1212/01.WNL.0000152051.18941.01
Muhammad S. Hussain
MD
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Ashfaq Shuaib
MD
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Zaeem A. Siddiqi
MD, PhD
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Citation
Spinal cord transient ischemic attacks: A possible role for abciximab
Muhammad S. Hussain, Ashfaq Shuaib, Zaeem A. Siddiqi
Neurology Feb 2005, 64 (4) 761-762; DOI: 10.1212/01.WNL.0000152051.18941.01

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Spinal cord TIAs can occur with aortic dissection, after aortic surgery, or with severe aortic atherosclerosis.1,2 Previous reports have focused mainly on the diagnosis and postmortem findings, and have not documented the role, if any, of thrombolysis, anticoagulation, or antiplatelet therapy in these patients.

Case report.

A 53-year-old man had three sudden episodes over a week of lower extremity weakness, bladder incontinence, and saddle anesthesia lasting 15 to 45 minutes, some accompanied by numbness and paresthesias around his buttocks. His past history was remarkable for treated hypertension and heavy smoking. His neurologic examination was relatively normal. Arterial pulses in legs were severely diminished and the dorsalis pedis pulsations could only be detected with a Doppler scan. Over the next 3 days, the episodes increased in severity and frequency, precipitated initially by activity but progressing to occur at rest. Along with saddle anesthesia he had loss of bladder control and transient leg weakness lasting several minutes …

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