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March 17, 2009; 72 (11) Correspondence

Neuropathology of brain death in the modern transplant era

Calixto Machado, Julius Korein
First published March 16, 2009, DOI: https://doi.org/10.1212/01.wnl.0000339394.33719.76
Calixto Machado
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Julius Korein
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Neuropathology of brain death in the modern transplant era
Calixto Machado, Julius Korein
Neurology Mar 2009, 72 (11) 1028; DOI: 10.1212/01.wnl.0000339394.33719.76

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To the Editor:

In this interesting article, Wijdicks and Pfeifer1 again review the neuropathologic findings in brain dead patients. They also acknowledge that improved organ transplant processes have shortened the required time to brain fixation in autopsies.1 It is true that the classic description of the “respirator brain” occurred when organ transplant protocols were not fully developed.2

We would like to add some remarks about the neuropathologic findings in the spine in brain death (BD). By the use of short latency somatosensory evoked potential (SEPs) in brain dead patients stimulating the median nerve, we found in one case no somatosensory components after P9 N9–Erb potential in any of the cephalic and non-cephalic derivations. This patient had an intracerebral hemorrhage and had been diagnosed brain …

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