Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis
Citation Manager Formats
Make Comment
See Comments

This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Abstract
Objectives: We reviewed the literature on IV stroke thrombolysis for patients with recent myocardial infarction (MI).
Methods: We searched PubMed and Ovid databases, relevant trials, and guidelines.
Results: Only 5 thrombolyzed stroke patients with recent MI were reported to have cardiac tamponade. Pathological studies show MI healing is completed by 7 weeks.
Conclusion: The time window from MI as a contraindication for IV stroke thrombolysis may be narrowed from 3 months in current guidelines to 7 weeks.
Footnotes
-
- MI
- myocardial infarction
-
Editorial, page 1780
- Received June 28, 2010.
- Accepted November 22, 2010.
- Copyright © 2011 by AAN Enterprises, Inc.
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)
Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here
Purchase
Individual access to articles is available through the Add to Cart option on the article page. Access for 1 day (from the computer you are currently using) is US$ 39.00. Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means. The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use. Distributing copies (electronic or otherwise) of the article is not allowed.
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
- Article
- Abstract
- POST-MI STROKE
- MI AS AN EXCLUSION CRITERION IN STROKE THROMBOLYTIC GUIDELINES AND TRIALS
- CARDIAC RUPTURE AFTER IV STROKE THROMBOLYSIS
- RISKS OF HEMOPERICARDIUM FOLLOWING MI THROMBOLYSIS
- MECHANISM OF HEMOPERICARDIUM AND CARDIAC RUPTURE WITH THROMBOLYSIS
- WINDOW OF RISK FOR HEMOPERICARDIUM AND CARDIAC RUPTURE
- RISK STRATIFICATION
- CURRENT OPTIONS
- DISCUSSION
- DISCLOSURE
- Footnotes
- REFERENCES
- Info & Disclosures
Dr. Dennis Bourdette and Dr. Lindsey Wooliscroft
► Watch
Related Articles
Topics Discussed
Alert Me
Recommended articles
-
Clinical and Ethical Challenges
Contraindications to intravenous rtPA for acute strokeA critical reappraisalJennifer E. Fugate, Alejandro A. Rabinstein et al.Neurology: Clinical Practice, June 10, 2013 -
Article
IV thrombolysis in very severe and severe ischemic strokeResults from the SITS-ISTR RegistryMichael V. Mazya, Kennedy R. Lees, David Collas et al.Neurology, November 06, 2015 -
Articles
Subtherapeutic warfarin therapy entails an increased bleeding risk after stroke thrombolysisMichael Ruecker, Benjamin Matosevic, Peter Willeit et al.Neurology, May 30, 2012 -
Articles
Prevalence of MRI-defined recent silent ischemia and associated bleeding risk with thrombolysisM. Tisserand, L. Le Guennec, E. Touzé et al.Neurology, March 09, 2011


