Isolated acquired primary gusto-lacrimal reflex from a brainstem glioma
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The gusto-lacrimal reflex, also known as Bogorad syndrome, is an autonomic synkinesia in which patients tear excessively in response to salivary stimuli.1,2 It most often results from aberrant reinnervation following acute idiopathic or traumatic facial nerve palsy. In rare cases, it occurs as a primary phenomenon in the setting of a slow-growing lesion, such as a vestibular schwannoma or meningioma in the internal auditory canal, that compresses or infiltrates the nerve.3,4 We describe a patient with gusto-lacrimal reflex without other evidence of facial nerve dysfunction from a low-grade glioma infiltrating the brainstem and cerebellum.
Footnotes
Author contributions: Both authors contributed equally to writing and revising the manuscript. A.K. obtained the MRI. N.R.M. arranged for the artist's drawings.
Study funding: No targeted funding reported.
Disclosures: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.
- Received January 16, 2013.
- Accepted in final form July 16, 2013.
- © 2013 American Academy of Neurology
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