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June 10, 2014; 82 (23) Clinical/Scientific Notes

Rapid development of 9 cerebral aneurysms in varicella-zoster virus vasculopathy

Ava L. Liberman, Maria A. Nagel, Michael C. Hurley, Frances Z. Caprio, Richard A. Bernstein, Don Gilden
First published May 14, 2014, DOI: https://doi.org/10.1212/WNL.0000000000000503
Ava L. Liberman
From the McGaw Medical Center of Northwestern University (A.L.L., M.C.H., F.Z.C., R.A.B.), Chicago, IL; and the University of Colorado School of Medicine (M.A.N., D.G.), Aurora.
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Maria A. Nagel
From the McGaw Medical Center of Northwestern University (A.L.L., M.C.H., F.Z.C., R.A.B.), Chicago, IL; and the University of Colorado School of Medicine (M.A.N., D.G.), Aurora.
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Michael C. Hurley
From the McGaw Medical Center of Northwestern University (A.L.L., M.C.H., F.Z.C., R.A.B.), Chicago, IL; and the University of Colorado School of Medicine (M.A.N., D.G.), Aurora.
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Frances Z. Caprio
From the McGaw Medical Center of Northwestern University (A.L.L., M.C.H., F.Z.C., R.A.B.), Chicago, IL; and the University of Colorado School of Medicine (M.A.N., D.G.), Aurora.
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Richard A. Bernstein
From the McGaw Medical Center of Northwestern University (A.L.L., M.C.H., F.Z.C., R.A.B.), Chicago, IL; and the University of Colorado School of Medicine (M.A.N., D.G.), Aurora.
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Don Gilden
From the McGaw Medical Center of Northwestern University (A.L.L., M.C.H., F.Z.C., R.A.B.), Chicago, IL; and the University of Colorado School of Medicine (M.A.N., D.G.), Aurora.
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Citation
Rapid development of 9 cerebral aneurysms in varicella-zoster virus vasculopathy
Ava L. Liberman, Maria A. Nagel, Michael C. Hurley, Frances Z. Caprio, Richard A. Bernstein, Don Gilden
Neurology Jun 2014, 82 (23) 2139-2141; DOI: 10.1212/WNL.0000000000000503

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This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.

A patient with zoster in multiple dermatomes, severe headache, and normal magnetic resonance angiography (MRA) and 4-vessel digital subtraction angiogram (DSA) developed 9 anterior circulation aneurysms 2 months later. Antiviral treatment resulted in clinical improvement, size reduction of most aneurysms, and complete resolution of the 2 largest aneurysms.

Acknowledgments

Acknowledgment: The authors thank Marina Hoffman for reviewing the manuscript for errors in grammar, punctuation, spelling, readability, clarity, and accuracy.

Footnotes

  • Author contributions: Drs. Liberman, Hurley, Caprio, Bernstein, Nagel, and Gilden all contributed to drafting/revising the manuscript for content, study concept/design, analysis or interpretation of data, vital reagents/tools/patents, and acquisition of data.

  • Study funding: Supported in part by NIH grants AG006127 and AG032958 to D.G. and NS067070 to M.A.N.

  • Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.

  • Received November 20, 2013.
  • Accepted in final form March 3, 2014.
  • © 2014 American Academy of Neurology
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