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September 02, 2014; 83 (10) Article

Feasibility of using an online tool to assess appropriateness for an epilepsy surgery evaluation

Jodie I. Roberts, Chantelle Hrazdil, Samuel Wiebe, Khara Sauro, Alexandra Hanson, Paolo Federico, Neelan Pillay, William Murphy, Michelle Vautour, Nathalie Jetté
First published August 8, 2014, DOI: https://doi.org/10.1212/WNL.0000000000000750
Jodie I. Roberts
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Chantelle Hrazdil
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
MD
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Samuel Wiebe
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Khara Sauro
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Alexandra Hanson
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Paolo Federico
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Neelan Pillay
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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William Murphy
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Michelle Vautour
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Nathalie Jetté
From the Department of Clinical Neurosciences and Hotchkiss Brain Institute (J.I.R., C.H., S.W., K.S., A.H., P.F., N.P., W.M., M.V., N.J.), Department of Community Health Sciences and Institute for Public Health (J.I.R., S.W., K.S., N.J.), and Department of Radiology (P.F.), University of Calgary; and Department of Medicine (C.H.), Division of Neurology, University of British Columbia, Canada.
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Citation
Feasibility of using an online tool to assess appropriateness for an epilepsy surgery evaluation
Jodie I. Roberts, Chantelle Hrazdil, Samuel Wiebe, Khara Sauro, Alexandra Hanson, Paolo Federico, Neelan Pillay, William Murphy, Michelle Vautour, Nathalie Jetté
Neurology Sep 2014, 83 (10) 913-919; DOI: 10.1212/WNL.0000000000000750

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Abstract

Objectives: To examine the applicability of applying an online tool to determine the appropriateness of referral for an epilepsy surgical evaluation and to determine whether appropriateness scores are concordant with the clinical judgment of epilepsy specialists.

Methods: We prospectively applied the tool in 107 consecutive patients with focal epilepsy seen in an epilepsy outpatient clinic. Variables collected included seizure type, epilepsy duration, seizure frequency, seizure severity, number of antiepileptic drugs (AEDs) tried, AED-related side effects, and the results of investigations. Appropriateness ratings were then compared with retrospectively collected information concerning whether a surgical evaluation had been considered.

Results: Thirty-nine patients (36.4%) were rated as appropriate for an epilepsy surgical evaluation, all of whom had adequately tried 2 or more appropriate AEDs. The majority of patients (84.6%) rated as appropriate had previously been considered or referred for an epilepsy surgical evaluation. Tool feasibility of use was high, with the exception of assessing whether previous AED trials had been adequate and discrepancies between physician and patient reports of AED side effects.

Conclusions: Our evidence-based, online clinical decision tool is easily applied and able to determine whether patients with focal epilepsy are appropriate for a surgical evaluation. Future validation of this tool will require application in clinical practice and assessment of potential improvements in patient outcomes.

GLOSSARY

AED=
antiepileptic drug;
CASES=
Canadian Appropriateness of Epilepsy Surgery;
SMU=
seizure monitoring unit;
UCLA=
University of California, Los Angeles

Footnotes

  • Go to Neurology.org for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

  • Supplemental data at Neurology.org

  • Received November 20, 2013.
  • Accepted in final form May 27, 2014.
  • © 2014 American Academy of Neurology
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