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Spontaneous intracranial hypotension (SIH) is an important cause of new daily persistent headaches.1 In most patients, the underlying cause is a CSF leak, always at the level of the spine.2 Once escaped into the epidural space, CSF is rapidly absorbed by the spinal epidural venous plexus, which is often maximally dilated in the setting of SIH. With conventional imaging, the presence of contrast in epidural veins has not been demonstrated in SIH, but indirect evidence for rapid venous absorption such as contrast in the renal collection system on CT myelography or early activity of tracer in the bladder on nuclear cisternography is common.1 We report the radiographic demonstration of direct CSF–venous fistulae in patients with SIH using digital subtraction myelography (DSM). DSM allows real-time high-resolution imaging of contrast injected through a lumbar puncture.3–5
Footnotes
Author contributions: Dr. Schievink: drafting/revising the manuscript, study concept or design, analysis or interpretation of data. Dr. Moser: drafting/revising the manuscript, study concept or design, analysis or interpretation of data. Dr. Maya: drafting/revising the manuscript, study concept or design, analysis or interpretation of data.
Study funding: No targeted funding reported.
Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.
- Received October 4, 2013.
- Accepted in final form March 13, 2014.
- © 2014 American Academy of Neurology
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