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Just as a person's qualifications can provide only a guide to their future job performance in the context of an interview, so with many medical conditions that have a genetic basis: the exact DNA alteration can only be a guide to predicting the severity of clinical expression in each case. It is the degree of expression that can be all-important for someone inheriting the condition, particularly when that expression may vary within a family.
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- © 2014 American Academy of Neurology
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