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Childhood precursors of adult diseases are increasingly identified by studies that span the period from birth to senescence. This is particularly relevant for cerebrovascular disease, for which links have been discovered with childhood obesity and adolescent-onset hypertension.1 In this issue of Neurology®, Poidvin et al.2 report an increased risk of stroke in adults treated with growth hormone (GH) during childhood. This report has been much anticipated by the endocrinology community because it extends and clarifies findings in a 2012 study showing increased mortality in adults treated in childhood with GH from the prospective European cohort study—the Safety and Appropriateness of Growth Hormone Treatments in Europe (SAGhE).3
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- © 2014 American Academy of Neurology
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- Childhood prescursors of adult stroke and growth hormone therapy
- Early recognition of high risk patients using Biophysical Semeiotics Tests
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