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March 31, 2015; 84 (13) Article

A Canada-wide survey of chronic respiratory disease and spinal cord injury

Jacquelyn J. Cragg, Freda M. Warner, John K. Kramer, Jaimie F. Borisoff
First published February 27, 2015, DOI: https://doi.org/10.1212/WNL.0000000000001428
Jacquelyn J. Cragg
From the School of Population and Public Health, Faculty of Medicine (J.J.C.), International Collaboration on Repair Discoveries (J.J.C., J.K.K., J.F.B.), and School of Kinesiology (J.K.K.), University of British Columbia, Vancouver; Simon Fraser University (F.M.W.), Burnaby; and British Columbia Institute of Technology (J.F.B.), Burnaby, Canada.
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Freda M. Warner
From the School of Population and Public Health, Faculty of Medicine (J.J.C.), International Collaboration on Repair Discoveries (J.J.C., J.K.K., J.F.B.), and School of Kinesiology (J.K.K.), University of British Columbia, Vancouver; Simon Fraser University (F.M.W.), Burnaby; and British Columbia Institute of Technology (J.F.B.), Burnaby, Canada.
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John K. Kramer
From the School of Population and Public Health, Faculty of Medicine (J.J.C.), International Collaboration on Repair Discoveries (J.J.C., J.K.K., J.F.B.), and School of Kinesiology (J.K.K.), University of British Columbia, Vancouver; Simon Fraser University (F.M.W.), Burnaby; and British Columbia Institute of Technology (J.F.B.), Burnaby, Canada.
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Jaimie F. Borisoff
From the School of Population and Public Health, Faculty of Medicine (J.J.C.), International Collaboration on Repair Discoveries (J.J.C., J.K.K., J.F.B.), and School of Kinesiology (J.K.K.), University of British Columbia, Vancouver; Simon Fraser University (F.M.W.), Burnaby; and British Columbia Institute of Technology (J.F.B.), Burnaby, Canada.
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Citation
A Canada-wide survey of chronic respiratory disease and spinal cord injury
Jacquelyn J. Cragg, Freda M. Warner, John K. Kramer, Jaimie F. Borisoff
Neurology Mar 2015, 84 (13) 1341-1345; DOI: 10.1212/WNL.0000000000001428

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Abstract

Objective: The objective of this study was to evaluate the association between chronic respiratory diseases (asthma and chronic obstructive pulmonary disease) and spinal cord injury (SCI) in a large representative sample.

Methods: Data were compiled from more than 60,000 individuals from the 2010 cycle of the cross-sectional Canadian Community Health Survey (CCHS). Multivariable logistic regression analysis was conducted to examine this relationship, adjusting for confounders, and using probability weighting to account for the CCHS sampling method.

Results: After adjusting for age, sex, and smoking status, SCI was associated with a significant increased odds of asthma (adjusted odds ratio = 1.59 [95% confidence interval 1.11, 2.26]; p < 0.05) and chronic obstructive pulmonary disease (1.87 [1.20, 2.91]; p < 0.05).

Conclusions: These heightened odds highlight the exigent need for targeted interventions and prevention strategies for respiratory health among individuals with SCI.

GLOSSARY

CCHS=
Canadian Community Health Survey;
CI=
confidence interval;
COPD=
chronic obstructive pulmonary disease;
OR=
odds ratio;
SCI=
spinal cord injury

Footnotes

  • Go to Neurology.org for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

  • Received September 18, 2014.
  • Accepted in final form December 9, 2014.
  • © 2015 American Academy of Neurology
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