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September 13, 2016; 87 (11) Article

Comment: Dual tasks as a sensitive measure of cognitive deficits in MS

Nils Muhlert
First published August 12, 2016, DOI: https://doi.org/10.1212/WNL.0000000000003105
Nils Muhlert
From the School of Psychological Science, University of Manchester, UK.
PhD
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Comment: Dual tasks as a sensitive measure of cognitive deficits in MS
Nils Muhlert
Neurology Sep 2016, 87 (11) 1090; DOI: 10.1212/WNL.0000000000003105

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Dual task paradigms are gaining traction as a means of detecting subtle cognitive deficits. By dividing performance between 2 separate tasks, they can highlight early cognitive changes, possible hallmarks of later deterioration. In the literature on dementia, dual task conditions differentiate between healthy controls and those with mild cognitive impairment, despite equivalent performance in single task conditions.1 In multiple sclerosis (MS), these early markers look increasingly advantageous. Roughly half of all people with MS go on to develop cognitive impairment, and with this comes increased risk of unemployment, social difficulties, and reduced quality of life.

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  • Study funding: No targeted funding reported.

  • Disclosure: Dr. Muhlert serves on the editorial board for Neurology® and receives/has received research support from the Wellcome Trust, Health and Care Research Wales, and the Biotechnology and Biological Sciences Research Council. Go to Neurology.org for full disclosures.

  • © 2016 American Academy of Neurology
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