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Epilepsy is a complex brain disorder that exerts distinct effects on neurodevelopment, behavior, and quality of life, depending on the timing of its onset across the life span. Seizures remain the defining feature of the clinical diagnosis of epilepsy. However, there has been a recent shift from classifying and understanding epilepsy based on seizure types to a more phenomenologic and syndromal approach, emphasizing a disruption of networks as a cause of seizures, in addition to well-known comorbidities in cognition and behavior.1 While the development of functional neuroimaging has provided substantial insights into the composition and characteristics of neuroanatomical networks responsible for the development of seizures,2 neuropsychological assessment, with the use of well-standardized neurocognitive and psychological tests, continues to provide the most validated and effective means of evaluating cognition and behavior in patients with epilepsy, in addition to other neurologic disorders.3
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See page 1642
- © 2016 American Academy of Neurology
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