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October 09, 2018; 91 (15) Disputes & Debates: Editors' Choice

Author response: The nature of postural tremor in Parkinson disease

Rick C. Helmich, Mark Hallett, Michiel F. Dirkx
First published October 8, 2018, DOI: https://doi.org/10.1212/WNL.0000000000006314
Rick C. Helmich
(Nijmegen, the Netherlands)
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Mark Hallett
(Bethesda)
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Michiel F. Dirkx
(Nijmegen, the Netherlands)
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Author response: The nature of postural tremor in Parkinson disease
Rick C. Helmich, Mark Hallett, Michiel F. Dirkx
Neurology Oct 2018, 91 (15) 724; DOI: 10.1212/WNL.0000000000006314

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We appreciate Dr. Jankovic's comments on our recently published article.1 Our findings suggest that reemergent tremor is fundamentally the same as resting tremor. In our cohort (n = 48), the average latency between movement and tremor reemergence was 15.9 seconds. The latency varied considerably (1 to >60 seconds) but was not associated with disease or tremor severity. Recent work suggests that reafference from voluntary movements may reset tremor,2 but other mechanisms may also apply.3

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  • Author disclosures are available upon request (journal{at}neurology.org).

  • See Editors' Note

  • See letter

  • Received August 10, 2018.
  • Accepted in final form August 10, 2018.
  • © 2018 American Academy of Neurology
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