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March 02, 2021; 96 (9) Editorial

Neuroimaging for Spontaneous Intracranial Hypotension Turned on Its Side

Ian Richard Carroll, Deborah I. Friedman
First published January 20, 2021, DOI: https://doi.org/10.1212/WNL.0000000000011518
Ian Richard Carroll
From the Department of Anesthesiology, Perioperative, and Pain Medicine (I.R.C.) and Stanford CSF Leak Headache Program (I.R.C.), Stanford Headache Clinic, Stanford School of Medicine, CA; and Departments of Neurology and Ophthalmology (D.I.F.), University of Texas Southwestern Medical Center, Dallas.
MD, MS
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Deborah I. Friedman
From the Department of Anesthesiology, Perioperative, and Pain Medicine (I.R.C.) and Stanford CSF Leak Headache Program (I.R.C.), Stanford Headache Clinic, Stanford School of Medicine, CA; and Departments of Neurology and Ophthalmology (D.I.F.), University of Texas Southwestern Medical Center, Dallas.
MD, MPH
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Neuroimaging for Spontaneous Intracranial Hypotension Turned on Its Side
Ian Richard Carroll, Deborah I. Friedman
Neurology Mar 2021, 96 (9) 415-416; DOI: 10.1212/WNL.0000000000011518

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Spontaneous intracranial hypotension (SIH) is a leading identifiable cause of a new daily persistent headache, typically either orthostatic or developing in the latter half of the day. Many other symptoms may be present, and the marked variability in phenotype between patients often leads to a delay in diagnosis. For many patients, initial diagnostic imaging includes spinal imaging with highly T2-weighted MRI or magnetic resonance (MR) myelography based on early small case series suggesting that spinal MRI correlated well with findings on conventional CT myelogram.1,2 However, even in the most sophisticated and experienced centers, the rate of finding a leak on spinal MRI among patients clinically suspected of having a CSF leak is relatively low when prospectively collected and evaluated.3

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  • Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the editorial.

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  • © 2021 American Academy of Neurology
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