马修斯等[1]试图区分血清反应阳性的视Neuromyelitis谱系障碍(NMOSD)基于大脑MRI女士记录。他们建议这些NMOSD患者大脑MRI表现出“道森的手指”。詹姆斯·道森描述这些特征病变病理女士“楔形地区广泛心室,基础和扩展到相邻组织的形式像手指一样的流程或壶腹,在每个中央船通常被发现。”[2] Ultra-high field MR allows for in vivo visualization of small central veins within 'Dawson's fingers'. Our two groups used ultra-high field MR to image brains in NMOSD and MS and independently reported that periventricular lesions are rare in NMOSD and lack central venule. [3,4]. This supports the authors’ finding that the presence of 'Dawson's fingers' constitutes strong evidence against the diagnosis of NMOSD. However, for this criterion to be useful in clinical practice, an unambiguous definition of what constitutes 'Dawson's finger' on conventional brain MRI must be adopted. It would be helpful if the authors could supply a definition based on their experience with NMOSD and MS that would more formally specify lesion morphology. This should include details on borders, dimensions, and orientation on axial and sagittal T2-weighted sequences. In addition, a defined distance from lateral ventricles and other periventricular lesions would be helpful.
马修斯等[1]试图区分血清反应阳性的视Neuromyelitis谱系障碍(NMOSD)基于大脑MRI女士记录。他们建议这些NMOSD患者大脑MRI表现出“道森的手指”。詹姆斯·道森描述这些特征病变病理女士“楔形地区广泛心室,基础和扩展到相邻组织的形式像手指一样的流程或壶腹,在每个中央船通常被发现。”[2] Ultra-high field MR allows for in vivo visualization of small central veins within 'Dawson's fingers'. Our two groups used ultra-high field MR to image brains in NMOSD and MS and independently reported that periventricular lesions are rare in NMOSD and lack central venule. [3,4]. This supports the authors’ finding that the presence of 'Dawson's fingers' constitutes strong evidence against the diagnosis of NMOSD. However, for this criterion to be useful in clinical practice, an unambiguous definition of what constitutes 'Dawson's finger' on conventional brain MRI must be adopted. It would be helpful if the authors could supply a definition based on their experience with NMOSD and MS that would more formally specify lesion morphology. This should include details on borders, dimensions, and orientation on axial and sagittal T2-weighted sequences. In addition, a defined distance from lateral ventricles and other periventricular lesions would be helpful.
1。马修斯L, Marasco R,尹浩然,詹金森。区别的血清反应阳性的动谱系障碍和脑损伤分布。女士首页神经学2013;80:1330 - 1337。
2。道森JW。播散性硬化症的组织学。1916年爱丁堡皇家学会的事务;50:621。
3所示。Sinnecker T,多尔J, Pfueller CF,等。不同的病变形态在7 T MRI视neuromyelitis有别于多发性硬化症。首页Neurology2012; 79:708 - 714。
4所示。kist我,赫伯特·J,通用电气周Y, Y Ultrahigh-Field先生(7 ? T)成像的大脑病变Neuromyelitis视。乘sci Int 2013; 2013:398259。doi: 10.1155 / 2013/398259。
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