PT -期刊文章盟Joohi Jimenez-Shahed AU -苏珊Bressman AU -米歇尔Burack盟-伊莱Farace AU -詹姆斯•杰•麦克伦尼AU -詹姆斯·柯克盟瑞秋Saunders-Pullman AU -杰森Schwalb盟Ludy施盟-梅雷迪斯•斯宾德勒盟-埃琳娜·莫罗盟-米歇尔纽约TI - RAD-PD:注册DBS促进帕金森病(P4.064) DP - 2018年4月10 TA -神经病学PG - P4.064 VI - 90 IP - 15补充4099 - //www.ez-admanager.com/content/90/15_Supplement/P4.064.short 4100 - //www.ez-admanager.com/content/90/15_Supplement/P首页4.064.full所以Neurology2018 4月10;90 AB -目的:描述一个脑深部电刺激(DBS)注册表建议的目的提高DBS疗法和帕金森病(PD)患者的治疗结果。背景:尽管大量证据支持DBS在继续最好的医疗管理在麻烦的运动并发症出现在PD,变化的结果不是很好理解,最佳实践是不明确的,和潜在的长期的健康经济数据和处理技术比较缺乏。随机试验是不切实际的探讨这些问题。设计/方法:调查潜在的临床基地调查临床数据通常被俘。RAD-PD设计作为质量改进的努力。一个大型和异构PD组进行DBS将前瞻性,全面使用标准评估电池和图像分析的特点。Clinician-measured和病人报告结果和成像将从超过1000个参与者聚集在40临床基地在5年的DBS疗法。结果:在25网站回应,96%完成一个MDS-UPDRS第三部分,70 - 77%完成我MDS-UPDRS部分,第二和第四,91%完成Hoehn Yahr登台,85%完成MoCA手术前。绝大多数不系统地评估非症状或冲动控制障碍,只有68%捕获PDQ-39。 No respondents assess operative risk or patient satisfaction. A comprehensive set of data elements was devised to be systematically captured and benchmarked for analysis in RAD-PD. Dashboarding to participating sites will enable them to consider implementing changes in therapeutic strategies to improve the quality of DBS care and outcomes for PD patients.Conclusions: RAD-PD is needed to prospectively capture standard and comprehensive assessments in a large PD cohort undergoing DBS, with the primary goal of improving DBS therapy and outcomes. Results will have broad applicability to a range of practice scenarios and patient characteristics and the infrastructure can be applied to other disease states.Study Supported by: Michael J Fox Foundation, Parkinson Study GroupDisclosure: Dr. Jimenez-Shahed has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Teva, St. Jude Medical, Medtronic. Dr. Jimenez-Shahed has received research support from Avid Radiopharmaceuticals, Acadia Pharmaceuticals, St. Jude Medical, Biotie, Michael J. Fox Foundation. Dr. Bressman has nothing to disclose. Dr. Burack has nothing to disclose. Dr. Farace has nothing to disclose. Dr. McInerney has nothing to disclose. Dr. Kirk has nothing to disclose. Dr Saunders-Pullman has nothing to disclose. Dr. Schwalb has nothing to disclose. Dr. Shih has nothing to disclose. Dr. Spindler has nothing to disclose. Dr. Moro has nothing to disclose. Dr. York has nothing to disclose.