RT期刊文章SR电子T1艾滋病毒急性中风患者的临床特点(P5.102)摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯SP P5.102 VO 90 15补充A1 Hemil冈萨雷首页斯A1 Lakshmi战士A1 Fabian塞拉莫拉莱斯A1丹尼尔大米A1丽莎Diep A1迈克尔·凯利年2018 UL //www.ez-admanager.com/content/90/15_Supplement/P5.102.abstract AB目的:探讨流行病学、血管分布和作用的传统中风的危险因素在影响艾滋病毒阳性patientsBackground:中风是艾滋病患者的发病率和死亡率的主要原因。与艾滋病毒相关的血管病变被认为中风的发病机制中发挥重要作用。因素如病毒诱导炎症、机会性感染和pro-atherosclerotic抗逆转录病毒(ARV)药物的效果都与这个过程。设计/方法:我们进行了回顾性分析34例脑卒中诊断出患有艾滋病毒和在我们医院在2009年和2017年之间。我们获得了中风和流行病学数据关于艾滋病毒诊断。结果:发病时的年龄中位数是52年(范围24 - 78)有78%的男性。所有患者在抗逆转录病毒药物,75%为例病毒学抑制的时候中风。百分之八十六的中风是缺血性中风。前循环是最常见的血管领土47%的影响,其次是并发前后(28%)和后独自一人(25%)。成像的证据颅内动脉粥样硬化被发现在60%的病人血管研究。十分显著的减少值CD4细胞计数的时候中风(p = 0.092),后跟一个显著增加CD4细胞计数中值在90 - 270天以下(p = 0.049)。 Diabetes was present in 20% and 50% had hypertension. The median LDL was 97mg/dL (range 18–198) and 41% were smokers.Conclusions: Our study illustrates the burden of stroke in an HIV cohort despite good rates of virologic suppression and only modest presence of traditional risk factors. This, coupled with the finding of disproportionate intracranial atherosclerosis, suggests a possible role of HIV vasculopathy. Additionally, the decline in CD4 count at the time of stroke could suggest an increased risk of stroke in patients with lower CD4 count. We suggest additional controlled studies to explore this further.Disclosure: Dr. Gonzalez has nothing to disclose. Dr. Warrior has nothing to disclose. Dr. Sierra Morales has nothing to disclose. Dr. Rice has nothing to disclose. Dr. Diep has nothing to disclose. Dr. Kelly has nothing to disclose.

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