PT -期刊文章AU -米歇尔Leppert盟-詹姆斯·伯克AU -乔纳森·坎贝尔AU -蒂莫西·伯纳德盟Stefan Sillau AU -迈克尔Ho盟沙龙泊松TI -动脉粥样硬化危险因素流行在年轻人中风和急性心肌梗死(P6.248) DP - 2018年4月10 TA -神经病学PG - P6.248 VI - 90 IP - 15补充4099 - //www.ez-admanager.com/content/90/15_Supplement/P6.248.short 4100 - //www.ez-admanager.com/content/90/15_Supplement/首页P6.248.full所以Neurology2018 4月10;90 AB -目的:更好地了解动脉粥样硬化危险因素的作用(ARF)中风与急性心肌梗死(AMI)的年轻人。背景:ARF已知会导致中风和老年人AMI。然而,他们在年轻人中风的角色很大程度上是未知的。设计/方法:使用一个随机样本10%的商业数据库,我们分析了2001 - 2014年之间的所有新生15-45岁。ARF包括高血压、高脂血症和糖尿病是由1 2门诊或住院ICD-9索赔。个人申请首次中风或AMI住院被确定。对于中风或AMI患者,ARF前都要求诊断中风或AMI住院。哎呀泊松回归模型是用来计算中风的发病率比或AMI,控制了年龄和性别。结果:370万年的年轻人,3357年首次中风,和3020年首次AMI。整体平均年龄28岁,而首次中风和AMI的平均年龄是37岁至39岁,分别。52%的参与者整体是女性,而55%的中风和AMI组中有40%是女性。 Overall prevalence of ARF were low: 6.8% for hypertension, 2.3% for diabetes, and 6.8% for hyperlipidemia. The prevalence of all ARF were significantly higher in AMI than stroke (stroke: 53.7% hypertension, 20.9% diabetes, 41.1% hyperlipidemia; AMI: 67.4% hypertension, 23.1% diabetes, 70% hyperlipidemia). Patients with hypertension were 4.9 and 5.9 times more likely to have AMI and stroke, respectively. Similarly, stroke and AMI risk ratios were increased with diabetes (5.0 and 5.8 respectively) and hyperlipidemia (3.1 and 2.8 respectively).Conclusions: ARF are more strongly associated with AMI than stroke. The AMI cohort is older, more male and has a higher prevalence of ARFs. ARF pose a significant risk of strokes and AMI in young adults and aggressive prevention and risk factor management is advised.Study Supported by: American Heart Association, Bugher FoundationDisclosure: Dr. Leppert has nothing to disclose. Dr. Burke has nothing to disclose. Dr. Campbell has nothing to disclose. Dr. Bernard has nothing to disclose. Dr. Sillau has nothing to disclose. Dr. Ho has nothing to disclose. Dr. Leppert has nothing to disclose.

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