TY -的T1 Steroid-responsive脑病与自身免疫性甲状腺炎:一个案例报告(P1.154) JF -神经学乔-神经学六世- 90 - 15补充SP - P1.154盟安德烈斯·德·Leon-Benedetti AU -首页丹尼尔加宾风迪卢卡盟Sishir Mannava AU - Mohan Kottapally盟Leticia撕裂Y1 - 2018/04/10 UR - //www.ez-admanager.com/content/90/15_Supplement/P1.154.abstract N2 -目的:NABackground: Steroid-responsive脑病与自身免疫性甲状腺炎(SREAT)是一种罕见的疾病,只有不到300例文献报道。设计/方法:我们报告一例病人虚弱、脑病、癫痫、高热和高anti-thyroperoxidase (anti-TPO)抗体是成功治疗类固醇。结果:一位55岁男性被外部医院头痛和可能的焦点发作。发达进步精神状态恶化,随后,他瞬态的转变轻偏瘫和发烧。普通CT和MRI大脑有或没有对比稀松平常的。我们到达医院,病人发热和催眠的颈背的刚性,目光偏差,轻微的右侧与正常强度和奔袭弛缓性轻偏瘫痉挛状态。轻微震颤出现在右手休息以及广义反射减退。腰椎穿刺显示增加白细胞(1200)与中性优势(81%),增加蛋白质(133 mg / dl)和正常的葡萄糖。病人开始广谱抗生素和抗病毒药物脑膜脑炎的怀疑,然而脑脊液培养结果为阴性,患者没有明显改善抗菌治疗。进一步的传染病检查、自身免疫性面板和多种的研究-除了anti-TPO抗体水平升高(864国际单位/毫升)。诊断为SREAT被怀疑和四甲基强的松龙是5天,其次是口服强的松锥度,改善神经系统考试。放电后,病人的精神状态在基线只剩下轻度残余轻偏瘫在考试。 Three weeks later, level of anti-TPO antibody was 566 iu/ml.Conclusions: Our case provides a classic description of a rare and underdiagnosed encephalitis. The clinical presentation of encephalopathy in the setting of anti-thyroid antibodies and improvement with immunosuppressive therapy are to date the accepted criteria necessary to diagnose SREAT. Obtaining an early diagnosis is of paramount importance, as most of its features may be reversible with immunosuppressive therapy.Disclosure: Dr. De Leon Benedetti has nothing to disclose. Dr. Di Luca has nothing to disclose. Dr. Mannava has nothing to disclose. Dr. Kottapally has nothing to disclose. Dr. Tornes has nothing to disclose. ER -