TY -的T1 King-Devick测试(KDT)和视觉对比敏感度测试(VCS)的偏头痛:偏头痛攻击快速眼动的影响和视觉灵敏度(S43.004) JF -神经学乔-神经学六世- 90 - 15补充SP - S43.004盟Chia-Chun蒋盟- Amaal j·斯塔林盟David Dodick AU -朱莉安娜VanderPluym Y1 - 2018/04/10 UR 首页- //www.ez-admanager.com/content/90/15_Supplement/S43.004.abstract N2 -目的:检测中枢神经系统功能的改变使用KDT和风险投资通过展示不同在偏头痛发作时相比inter-ictal(攻击)之间的阶段。背景:偏头痛特点是头部疼痛和症状包括畏光和认知功能障碍在攻击。KDT是定时快速数字命名测试评估眼跳眼球运动,关注,信息处理,并对脑功能改变高度敏感。VCS措施在低对比度视觉分辨细节的能力水平。KDT与风投已被证明与神经功能障碍在各种神经系统疾病。设计/方法:我们包括成人主题情景或慢性偏头痛的先兆头痛(少于25天/月)。我们梅奥诊所登记现场员工,KDT与风投是由相同的考官减少偏见。对于每个参与者,我们执行KDT和偏头痛发作时,VCS在头痛阶段测试和inter-ictal非头痛阶段。权力分析显示26个科目需要检测的样本容量的大小产生影响0.8 KDT和vc,权力和80%显著性水平为0.05。主题由自己控制。结果:我们28日收集的数据对象。 There was a statistically significant difference in the performance of KDT during the migraine attack compared to the inter-ictal baseline. On average, the KDT score was 6.3 seconds longer during the migraine attack compared to the interictal baseline. For VCS (both 100% and 2.5% contrast sensitivity), there was no significant difference between the migraine attack and the inter-ictal baseline.Conclusions: This study provides objective and quantitative data demonstrating altered cerebral function during migraine attacks. The KDT could be an effective tool to understand migraine pathophysiology, to document the true interictal state, as well as to characterize migraine associated disability during and between attacks.Disclosure: Dr. Chiang has nothing to disclose. Dr. Starling has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Alder, Amgen, Eli Lilly & Company, eNeura. Dr. Dodick has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Acorda, Allergan, Amgen, Alder, Dr Reddy’s, Merck, Dr Reddy’s, Promius, eNeura, Eli Lilly & Company, Insys therapeutics, Autonomic Technologies, Teva, Xenon, Tonix, Trigemina, Boston Scientific, GBS, Colucid, Zosano, Laydenburg Thalmann, Biocentric, Biohaven, Magellan, Pfizer (Japan), Charleston Laboratories. Royalties: Oxford University Press and Cambridge University Press (Book Royalty). Uptodate — editorial/honoraria. CME companies honoraria/publishing honoraria/royalites: Chameleon Communications, Medscape, WebMD, Academy for Continued Healthcare Learning, Haymarket Medical Education, Miller Medical Communications, Global Scientific Communications, HealthLogix, Academy for Continued Healthcare Learning, Meeting LogiX, Health LogiX, . Dr. VanderPluym has nothing to disclose. ER -