PT -期刊文章盟马赛厄斯帕默AU -伦道夫·马歇尔盟Qixuan陈盟-凯文Slane盟-罗纳德•拉扎尔非盟-玫琳凯Pavol TI -认知在血流动力学衰竭患者由于严重颈动脉狭窄(p1.3 - 061) DP - 2019年4月09年TA -神经病学第六PG - p1.3 - 061 - 92 IP - 15补充4099 - //www.ez-admanager.com/content/92/15_supplement/p1.3 061. - 061.短4100 - //www.ez-admanager.com/首页content/92/15_supplement/p1.3 - -全所以Neurology2019 4月09年;92 AB -目的:我们研究了颈动脉狭窄之间的关系,血液动力学的失败,和认知特征认知严重颈动脉狭窄患者,有或没有血流动力学的失败。背景:严重颈动脉狭窄可以减少由于低灌注认知。发表的认知变量血管疾病的概况,然而,从而排除失败的血流动力学指标的识别一个特定的原因。设计/方法:六十一例患者(18与TIA,没有与中风)与颈动脉狭窄≥80%来自两组研究、侦察和BFC1。血流动力学状态评估使用氧气提取比例由正电子发射断层扫描(侦察)或平均流速通过经颅多普勒(黄东海和一分为二为正常(n = 30)对受损(n = 31)。认知与16个测试评估。16线性回归,一个用于每个认知测试,进行血流动力学的影响评估失败在考试分数,调整了闭塞,抑郁,年龄,性别,教育和研究对象。多个比较调整使用错误发现率(罗斯福)校正。结果:血流动力学的失败是雷伊复杂图测试副本的一个有效的独立预测指标(RCFT-C, p = 0.007), RCFT-Delayed召回(RCFT-D, p = 0.003),和小道Test-B (TMT-B, p = 0.006),罗斯福校正后仍然如此。其他测试没有预测的血流动力学状态。Conclusions: Tests of mental flexibility, visuospatial skill, and organization were sensitive to hemodynamic failure in patients with severe carotid stenosis. A larger sample is required to validate this cognitive profile in such patients. Cognitive assessment with RCFT-C, RCFT-D, and TMT-B may detect the effects of hemodynamic failure specific to large vessel disease, having research and treatment utility.Disclosure: Dr. Palmer has nothing to disclose. Dr. Marshall has nothing to disclose. Dr. Chen has nothing to disclose. Dr. Slane has nothing to disclose. Dr. Lazar has nothing to disclose. Dr. Pavol has nothing to disclose.