% 0期刊文章% Idrees Azher安德鲁% Ashutosh Kaushal % Chang % (Shawna削减%布莱恩Mac Grory %一个凯蒂Dakay蒂娜伯顿% %布拉德福德·汤普森%一个迈克尔Reznik %琳达温德尔%尼古拉斯·波特%一个亚历山大merkle阿里Mahta % % % Hooman卡米切尔艾尔金德%一个马赫什Jayaraman %迈克尔·Atalay %凯伦富里% Shadi Yaghi % T血清肌钙蛋白水平在急性缺血性中风识别患者伴随的内脏梗死(p2.3 - 030) % D J神经病学2019% % P p2.3 - 030 V % N % 15补充X 92%目的:确定血清肌钙蛋白水平之间的关系的时候中风和内脏缺血性中风组梗塞。首页背景:缺血性中风患者的cardioembolic起源、发展的风险内脏(肾、脾)梗塞。设计/方法:数据抽象从单中心前瞻性缺血性中风数据库超过18个月,包括缺血性中风患者进行了对比增强CT腹部和骨盆在一年内用于临床的中风。主要因素是肌钙蛋白水平≥0.1 ng / mL。主要结果是内脏梗死(肾和脾)CT腹部和骨盆。单变量和多变量逻辑回归模型被用来估计的优势比和95%置信区间(或者,95% CI)协会的肌钙蛋白与内脏梗死前后调整人口结构和危险因素(高血压、糖尿病、高脂血症、中风历史、充血性心力衰竭、冠心病、和吸烟),署分数,和中风亚型(cardioembolic、栓塞性中风的未知来源,并定义non-cardioembolic亚型)。结果:1234缺血性中风患者,259例有资格内脏CT。血清肌钙蛋白水平入院时测定237例(93.3%)。25内脏梗死患者:16个肾,7脾,2两。在单变量模型中,有一个协会之间的血清肌钙蛋白水平和存在的内脏梗死(39.1%比15.0%,p = 0.008),它保存在多变量模型(或3.65 95%可信区间1.46 - 9.17,p = 0.006)。毫不奇怪,有一个内脏梗死和cardioembolic中风亚型之间的联系(或7.88 95%可信区间1.01 - 61.87,p = 0.05)和、因亚型(95%可信区间0.95 - 60.15或7.55,p = 0.056),相比non-cardioembolic中风亚型。结论:缺血性中风患者,血清肌钙蛋白水平升高可能有助于识别患者伴随的内脏梗死。需要更大规模的研究来证实我们的发现。披露:Azher博士没有披露。 Dr. Kaushal has nothing to disclose. Dr. Chang has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. Mac Grory has nothing to disclose. Dr. Burton has nothing to disclose. Dr. Dakay has nothing to disclose. Dr. Thompson has nothing to disclose. Dr. Reznik has nothing to disclose. Dr. Wendell has nothing to disclose. Dr. Potter has nothing to disclose. Dr. Mahta has nothing to disclose. Dr. Merkler has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with GLG. Dr. Kamel has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Roivant Sciences, Medtronic, BMS, and Roche Diagnostics Corporation. Dr. Kamel has received personal compensation in an editorial capacity for JAMA Neurology. Dr. Kamel has received research support from NIH/NINDS. Dr. Elkind has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Abbott, Vascular Dynamics, Merck/Organon Auxilium, and Sorin. Dr. Elkind has received research support from BMS-Pfizer Alliance, and Roche. Dr. Jayaraman has nothing to disclose. Dr. Atalay has nothing to disclose. Dr. Furie has nothing to disclose. Dr. Yaghi has nothing to disclose. %U