% 0期刊文章%一个詹姆斯Siegler %史蒂文展览馆%海蒂Sucharew % Tapan Mehta %一个艾米Starosciak Niraj Arora % %费利佩•德洛里奥斯La Rosa %一个Akshitkumar Mistry娜塔莎威尔% %一个联合国开发Patel %萨尔曼·阿萨德%一个凯蒂Dakay阿姆土耳其帽% %一个杰夫·瓦格纳%艾丽西娅·班尼特% Bharathi Jagadeesan %斯图尔特韦伯克里斯托弗•Streib % % Rohan Chitale %一个约翰沃尔皮% Stephan Mayer % Shadi Yaghi % Mahesh Jayaraman % Pooja Khatri %缺血性核心的伊娃Mistry % T低估灌注CT在急性患者大血管闭塞:最好的前瞻性队列研究的结果(p5.3 - 050) % D J神经病学2019% % P p5.3 - 050 V % N % 15补充X 92%目的:确定之间的相关程度,unenhanced CT及CT灌注核心大血管闭塞患者的梗死体积。首页背景:2018年美国医院协会指南建议急性大血管闭塞患者的血栓切除术(LVO)被认为是基于灌注成像6到24小时的窗口。在6小时内,CT灌注(CTP)核心估计可能低估了不可逆转的梗死体积可视化unenhanced CT;然而这并没有在以后的时间窗口。设计/方法:采用多中心前瞻性群组的病人血栓切除术为LVO 0-24最后正常后几小时,我们相关的基线CTP核心梗塞体积(rCBF < 30%)和unenhanced CT方面得分。我们比较CTP发现患者之间一个不利的方面(< 6)对那些有有利的方面(≥6),随着时间的推移和评估结果。结果:443例,165人接受了CTP包括(平均年龄69 y, 50%女性,平均8 (IQR 6 - 9)和9 cc(差0-28))的核心。方面和核心卷适度相关(r =−0.35, p < 0.01)。一个没有核心(0 cc)是观察到32%的患者,其中方面得分中值为8 (IQR 8 - 10)。在调整年龄和基线署,方面得分显著下降随着时间的推移(和1.05,95%可信区间1.01 - -1.10,p = 0.01),而核心(p = 0.69)和半影卷(p = 0.74)保持不变。结论:在这个病人的多中心前瞻性群组血栓切除术,三分之一的患者正常核心梗塞卷尽管一半的病人显示不可逆转的梗死unenhanced CT(≤8)方面。 As time progresses, the unenhanced CT demonstrates evolution of irreversible infarction, whereas the perfusion core appears static. This finding emphasizes the need to carefully assess both unenhanced CT and CTP when considering thrombectomy eligibility in the late time window.Disclosure: Dr. Siegler has nothing to disclose. Dr. Messe has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Claret Medical, Inc. Dr. Messe has received research support from WL Gore & Associates, Bayer, and Mallinkrodt. Dr. Sucharew has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Arora has nothing to disclose. Dr. Starosciak has nothing to disclose. Dr. De Los Rios La Rosa has nothing to disclose. Dr. Barnhill has nothing to disclose. Dr. Mistry has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Assad has nothing to disclose. Dr. Tarboosh has nothing to disclose. Dr. Dakay has nothing to disclose. Dr. Wagner has nothing to disclose. Dr. Bennett has nothing to disclose. Dr. Jagadeesan has nothing to disclose. Dr. Streib has nothing to disclose. Dr. Weber has nothing to disclose. Dr. Chitale has nothing to disclose. Dr. Volpi has nothing to disclose. Dr. Mayer has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Idorsia, Edge, and NFL. Dr. Yaghi has nothing to disclose. Dr. Jayaraman has nothing to disclose. Dr. Khatri has nothing to disclose. Dr. Amin has nothing to disclose. %U