% 0期刊文章% Idrees Azher % Ashutosh Kaushal罗伯特·雷吉奥% %一个凯拉穆雷%斯科特·穆迪%萨曼莎科斯塔%一个布拉德福德·汤普森凯蒂Dakay % %琳达温德尔·迈克尔Reznik % %一个尼古拉斯·波特% Shyam Rao % Shadi Yaghi %布莱恩Mac Grory %一个蒂娜伯顿% (Shawna削减%瑞安-麦克塔加特% Mahesh Jayaraman %一个阿里Mahta凯伦富里% % T向上趋势早期白细胞计数可预测患者的不良预后动脉瘤性蛛网膜下腔出血(p5.9 - 041) % D J神经病学2019% % P p5.9 - 041 V % 92% N % X 15补充目的:研究早期向上趋势的白细胞的意义作为一个潜在的预测为贫困的结果还不清楚。首页背景:增加白细胞计数(WBC)早期在动脉瘤性蛛网膜下腔出血(aSAH表示)可以表明一个持续的炎症过程由最初的侮辱。设计/方法:回顾性队列研究从aSAH表示数据库三级转诊学术中心的病人承认从2015年到2018年。的白细胞每天前5天的住院治疗,狩猎和赫斯(HH)品位和临床数据包括改良Rankin规模(夫人)放电的时候被检索。向上趋势的白细胞被定义为任何增加白细胞从入学前五天内没有任何减少住院治疗。白细胞增多被定义为白细胞入院时大于每微升12000个细胞。可怜的结果被定义为夫人的4至6时放电。向上趋势的白细胞和糟糕的结果之间的关系是决定多元逻辑回归模型。结果:共有183名患者完成住院数据包括在内。贫穷率结果率为58%(43/74)患者的向上趋势的白细胞和48%(53/109)的患者没有向上趋势的白细胞。可怜的结果,患者的61%(69/112)已经在24小时内白细胞增多。二次分析患者的白细胞增多,80%(53/66)的患者最初的WBC大于15000贫穷的结果。早期向上趋势的白细胞低下显著相关,多元分析的结果,它是独立于入学HH品位和白细胞增多(优势比= 2.36 (95% CI 1.12 - -4.96); p=0.023).Conclusions: Uptrending WBC early course of hospitalization can be an independent predictor of poor outcome in patients with aSAH. Further investigations to explore treatment modalities targeting neuro-inflammation in patients with SAH should be sought.Disclosure: Dr. Azher has nothing to disclose. Dr. Riggio has nothing to disclose. Dr. Kaushal has nothing to disclose. Dr. Murray has nothing to disclose. Dr. Moody has nothing to disclose. Dr. Costa has nothing to disclose. Dr. Dakay has nothing to disclose. Dr. Thompson has nothing to disclose. Dr. Reznik has nothing to disclose. Dr. Wendell has nothing to disclose. Dr. Potter has nothing to disclose. Dr. Rao has nothing to disclose. Dr. Yaghi has nothing to disclose. Dr. Mac Grory has nothing to disclose. Dr. Burton has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. McTaggart has nothing to disclose. Dr. Jayaraman has nothing to disclose. Dr. Furie has nothing to disclose. Dr. Mahta has nothing to disclose. %U