伊丽莎白Spurgeon % 0期刊文章% % Stephen Hantus一个太阳之亚迪% % T癫痫手术结果脑炎的设定:一个案例系列(p5.5 - 023) % D J神经病学2019% % P p5.5 - 023 V % 92% N % X 15补充目的:研究结果三个设置的难治性癫痫脑炎患者癫痫手术。首页背景:癫痫手术是一种有效的治疗选择在医学上棘手的局灶性癫痫。然而,这种手术的价值在难治性癫痫患者脑炎的设置还没有完善。设计/方法:病例系列。案例1:28岁出现局灶性癫痫持续状态,被发现sero-negative脑炎和内侧颞硬化。地位是流产,但发作持续尽管5抗癫痫药物(AED)。他接受了正确的前颞叶切除术,然后立体声脑电图,其次是右颞回切除。他手术后癫痫复发,但现在是控制发作三年5日AED(恩格尔类I)实例2:37岁出现癫痫发作,发现sero-negative脑炎。她更频繁的癫痫发作,尽管3 AED和迷走神经刺激法。Stereo-EEG显示癫痫发作引起的左边中间的时间和正确的内侧额叶区域。她接受了左颞叶切除术。癫痫复发,但整体频率显著提高4 AED(恩格尔第三类)实例3:29岁出现癫痫持续状态,并发现sero-negative脑炎。 Status was stopped, but seizures continued despite 3 AED’s. Her seizure frequency increased to almost daily. Video-EEG monitoring and Stereo EEG showed seizures in bilateral fronto-temporal regions predominantly in left mesial temporal region. She had left temporal lobectomy, without improvement, requiring 4 AED’s (Engel Class IV).Conclusions: Case 1 had a well localized but multi-focal epilepsy and became seizure-free after two epilepsy surgeries. Cases 2 and 3 had multi-focal epilepsy; case 2 improved after surgery while case 3 did not. A detailed study looking at the surgical outcomes of patients with refractory seizures developing after encephalitis is needed.Disclosure: Dr. Spurgeon has nothing to disclose. Dr. Yardi has nothing to disclose. Dr. Hantus has nothing to disclose. %U

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