PT -期刊文章盟埃里克·赫希AU -杰克Gierlich盟埃里卡Glants AU - Tahir酋长盟达里尔·杜兰盟Ranga克里希纳TI -周期性呕吐与焦点相关的病变区域Postrema成功管理医用大麻(p3.9 - 053) DP - 2019年4月09年TA -神经病学第六PG - p3.9 - 053 - 92 IP - 15补充4099 - //www.ez-admanager.com/content/92/15_supplement/p3.9 053. - 053.短4100 - //www.ez-admanager.com/content首页/92/15_supplement/p3.9 - -全所以Neurology2019 4月09年;92 AB -目的:N /背景:焦的病变区域postrema很少报道引起的周期性呕吐和临床医生和放射科医生诊断挑战。虽然大麻类已被证明中央CB1/2受体,减少chemotherapy-associated呕吐,他们在其他呕吐障碍的角色不太确定。设计/方法:30岁的女性提出的神经学有着15年历史的诊所周期性呕吐。首页她经历了20天症状一个月,在此期间,她将呕吐物8倍的5 - 6小时。鼻舒马曲坦只提供了最小的救援,她经常在这些住院静脉水化的情节。一个广泛的检查在多个机构未能确定她呕吐的原因。神经是毋庸置疑。核磁共振成像的大脑被下令评估颅内病变。核磁共振最初阅读正常;然而,在审查,一个小中央hypointensity尾结束的第四脑室符合区域的局部病变postrema指出。 A repeat MRI four months later confirmed the finding.Results: Given a presumed central etiology for the vomiting and the limited success of conventional therapy, a trial of medical marijuana was recommended. The patient was prescribed 10mg of 1:1 CBD:THC daily with 30mg CBD to be taken at the onset of vomiting episodes. On this regimen, the frequency of episodes was reduced to 7 times a month and the duration was reduced to 3–5 hours. There were no further hospitalizations, and the patient reported significant improvement in quality of life.Conclusions: This case of a rare focal lesion of the area postrema highlights the importance of investigating central neurological causes in patients with persistent unexplained vomiting, even in the presence of a normal neurological exam, and the utility of marijuana in managing this broad spectrum of disease.Disclosure: Dr. Hirsch has nothing to disclose. Dr. Gierlich has nothing to disclose. Dr. Glants has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Duran has nothing to disclose. Dr. Krishna has nothing to disclose.