局长Mayra蒙塔沃% 0期刊文章% %一个Mahesh Jayaraman Aleksandra Yakhkind % %瑞安-麦克塔加特%罗纳德·Akiki Andrew Chang % %布莱恩Mac Grory % (Shawna削减%蒂娜伯顿%迈克尔Reznik %一个琳达·温德尔·布拉德福德·汤普森% % Shyam Rao %一个阿里Mahta尼古拉斯·波特% %约书亚开松机凯文Sheth % % Pooja Khatri %凯伦富里% Shadi Yaghi % T预测糖尿病症状性脑出血血栓切除术后急性缺血性中风(p1.3 - 035) % D J神经病学2019% % P p1.3 - 035 V % N % 15补充X 92%目标:我们的目标是确定糖尿病之间的关联和症状性脑出血(西奇)在接受机械血栓切除术的患者。首页背景:糖尿病对血管的完整性有有害的影响通过几种机制包括血脑屏障损伤,兴奋性趋化因子、酸中毒、和水肿。它一直伴随着(西奇)溶栓后政府对缺血性中风。设计/方法:数据抽象的罗德岛医院未来的中风患者注册,包括连续被选为血栓切除术在我们机构在一段时间内的24个月的目标识别西奇的危险因素。糖尿病的主要因素是历史,主要结果是西奇定义基于修改后的SITS-MOST标准署(实质血肿以及增加4分或更多)。我们比较基线特征和患者之间没有西奇使用单变量和多变量分析。统计分析了使用SPSS 20.0版和p值< 0.05是显著的。结果:307例,12例(3.9%)有经验的西奇。的平均年龄是73岁;49.2%都是男性。在单变量分析,糖尿病与西奇(50.0%比17.3%,p = 0.012)。本协会坚持多变量模型调整年龄、署得分,得分方面,时间再灌注,TICI得分(优势比为6.0,95%可信区间1.5 - -23.3,p = 0.011)。 We performed sensitivity analyses excluding patients who received intravenous tPA (n = 189) and the results remained unchanged (OR 8.5, 95% CI 0.84–83.3, p = 0.071).Conclusions: Diabetes mellitus is an independent predictors of sICH in patients with acute ischemic stroke undergoing mechanical thrombectomy, with or without IV tPA. More studies are needed to confirm our findings and to determine blood sugar control in the post-thrombectomy reduces this risk.Disclosure: Dr. Montalvo Perero has nothing to disclose. Dr. Yakhkind has nothing to disclose. Dr. Jayaraman has nothing to disclose. Dr. McTaggart has nothing to disclose. Dr. Chang has nothing to disclose. Dr. Akiki has nothing to disclose. Dr. Mac Grory has nothing to disclose. Dr. Cutting has nothing to disclose. Dr. Burton has nothing to disclose. Dr. Reznik has nothing to disclose. Dr. Thompson has nothing to disclose. Dr. Wendell has nothing to disclose. Dr. Rao has nothing to disclose. Dr. Potter has nothing to disclose. Dr. Mahta has nothing to disclose. Dr. Sheth has received royalty, license fees, or contractual rights payments from Alva Health. Dr. Sheth has received research support from Biogen, Novartis, Bard, and Hyperfine. Dr. Willey has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with MKSAP 18, American College of Physicians, Edwards Scientific, Medtronic, Grand Rounds Expert Care. Dr. Willey has received personal compensation in an editorial capacity for Uptodate.com. Dr. Khatri has nothing to disclose. Dr. Furie has nothing to disclose. Dr. Yaghi has nothing to disclose. %U