作者@article {edhip4.5 - 024 ={默罕默德·m·艾迪和布里吉特Angelini Maryum Shoukat所罗门卡萨岛和哈桑Aboul努尔Farrukh Javed和Elahe Bordbar和穆罕默德Tabaeizadeh Fesharaki贾斯汀·加拉格尔和苏菲s Stekhoven Valdery莫拉和金jj马诺Ghanta m .威斯多佛和萨哈尔征服者和埃里克·罗森塔尔},title ={发作的关系,Ictal-Interictal脑电图活动,临床结果和动态神经变化后创伤性脑损伤(p4.5 - 024)},体积={92}={15}补充数量,elocation-id = {p4.5 - 024} ={2019},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:癫痫发作和IIC异常(伙伴)创伤性脑损伤(TBI)后与贫穷相关的结果。首页我们检查了结构和动态特性检查病理生理学调节这种关系。背景:创伤性脑损伤后癫痫发作和伙伴是常见的。设计/方法:我们回顾性研究创伤性脑损伤患者进行连续脑电图(2013 {\ textendash} 2017)。电记录的癫痫发作和伙伴(单侧性的有节奏的三角洲或定期排放进行评估与clinicoradiologic特性(APACHE-II得分,contusional,硬膜下、硬膜外蛛网膜下腔室血肿),可怜的结果(放电戈斯1 {\ textendash} 2、GCS和动态变化测量在入学和脑电图。结果:108例创伤性脑损伤病人遇到标准;39(36.1 \ %)演示了癫痫发作或伙伴。在单变量分析中,癫痫的存在对cEEG与坏的24小时GCS, 24小时的GCS恶化,在入学和临床发作。逻辑回归,只有坏的gc(1.08或1.19,CI {\ textendash} 1.44, p = 0.02)和临床发作在入学(2.73或11.42,CI {\ textendash} 53.47, p = 0.001)是独立与电记录的发作有关。排除癫痫患者,伙伴的存在与年龄、性别、24小时GCS和SDH最差。年龄、GCS和SDH不再存在显著的多元变量分析。可怜的结果是独立的逻辑回归与相关APACHE-II得分(1.04或1.14,CI {\ textendash} 1.26, p = 0.004)和GCS恶化在脑电图监测(0.56或0.69,CI {\ textendash} 0.85, p = 0.001)。 GCS deterioration during EEG was greater when the following were present vs. absent: non-seizure IICA (mean change -1.4 vs. +0.80, p=0.001), and seizures (mean change -1.2 vs. +0.33, p=0.01). GCS deterioration was not different for the presence vs. absence of burst-suppression (mean change -0.40 vs. -0.27, p=0.45) or generalized rhythmic delta activity (mean change - 0.33 vs. +0.11, p=0.27).Conclusions: TBI patients with GCS deterioration are at highest risk for seizures after TBI. The association of seizures and IICA with neurologic deterioration appears to be one factor mediating their association with poor outcome.Disclosure: Dr. Edhi has nothing to disclose. Dr. Angelini has nothing to disclose. Dr. Shoukat has nothing to disclose. Dr. Kassa has nothing to disclose. Dr. Aboul Nour has nothing to disclose. Dr. Javed has nothing to disclose. Dr. Bordbar has nothing to disclose. Dr. Tabaeizadeh Fesharaki has nothing to disclose. Dr. Gallagher has nothing to disclose. Dr. Stekhoven has nothing to disclose. Dr. Moura has nothing to disclose. Dr. Jjing has nothing to disclose. Dr. Ghanta has nothing to disclose. Dr. Westover has nothing to disclose. Dr. Zafar has nothing to disclose. Dr. Rosenthal has nothing to disclose.}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/92/15_Supplement/P4.5-024}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }