PT -期刊文章AU -默罕默德·m·艾迪AU -布里吉特Angelini盟Maryum Shoukat AU -所罗门卡萨岛AU -哈桑Aboul努尔盟Farrukh Javed AU - Elahe Bordbar AU -穆罕默德Tabaeizadeh Fesharaki AU -贾斯汀•加拉格尔盟苏菲s Stekhoven盟Valdery莫拉非盟主席-金jj盟Ghanta AU - m .威斯多佛盟-萨哈尔征服者AU -埃里克·罗森塔尔TI -癫痫的关系,Ictal-Interictal脑电图活动,临床结果和动态神经变化后创伤性脑损伤(p4.5 - 024) DP - 2019年4月09年TA -神经病学第六PG - p4.5 - 024 - 92 IP - 15补充4099 - //www.ez-admanager.com/content/92/15_supplement/p4.5 024. - 024.短4100 - //www.ez-admanager.com/content/92/15_supplement/p4.5 - -全所以Neurology2019 4月09年;首页92 AB -目的:癫痫发作和IIC异常(伙伴)创伤性脑损伤(TBI)后与贫穷相关的结果。我们检查了结构和动态特性检查病理生理学调节这种关系。背景:创伤性脑损伤后癫痫发作和伙伴是常见的。设计/方法:我们回顾性研究创伤性脑损伤患者进行连续脑电图(2013 - 2017)。电记录的癫痫发作和伙伴(单侧性的有节奏的三角洲或定期排放进行评估与clinicoradiologic特性(APACHE-II得分,contusional,硬膜下、硬膜外蛛网膜下腔室血肿),可怜的结果(放电戈斯1 - 2,动态GCS测量在入学和脑电图的变化。结果:108例创伤性脑损伤病人遇到标准;39例(36.1%)显示癫痫或伙伴。在单变量分析中,癫痫的存在对cEEG与坏的24小时GCS, 24小时的GCS恶化,在入学和临床发作。逻辑回归,只有坏的gc(置信区间1.08 - -1.44或1.19,p = 0.02)和临床发作在入学(置信区间2.73 - -53.47或11.42,p = 0.001)是独立与电记录的发作有关。排除癫痫患者,伙伴的存在与年龄、性别、24小时GCS和SDH最差。年龄、GCS和SDH不再存在显著的多元变量分析。 Poor outcome was independently associated on logistic regression with APACHE-II score (OR 1.14, CI 1.04–1.26, p=0.004) and GCS deterioration during EEG monitoring (OR 0.69, CI 0.56–0.85, p=0.001). GCS deterioration during EEG was greater when the following were present vs. absent: non-seizure IICA (mean change −1.4 vs. +0.80, p=0.001), and seizures (mean change −1.2 vs. +0.33, p=0.01). GCS deterioration was not different for the presence vs. absence of burst-suppression (mean change −0.40 vs. −0.27, p=0.45) or generalized rhythmic delta activity (mean change − 0.33 vs. +0.11, p=0.27).Conclusions: TBI patients with GCS deterioration are at highest risk for seizures after TBI. The association of seizures and IICA with neurologic deterioration appears to be one factor mediating their association with poor outcome.Disclosure: Dr. Edhi has nothing to disclose. Dr. Angelini has nothing to disclose. Dr. Shoukat has nothing to disclose. Dr. Kassa has nothing to disclose. Dr. Aboul Nour has nothing to disclose. Dr. Javed has nothing to disclose. Dr. Bordbar has nothing to disclose. Dr. Tabaeizadeh Fesharaki has nothing to disclose. Dr. Gallagher has nothing to disclose. Dr. Stekhoven has nothing to disclose. Dr. Moura has nothing to disclose. Dr. Jjing has nothing to disclose. Dr. Ghanta has nothing to disclose. Dr. Westover has nothing to disclose. Dr. Zafar has nothing to disclose. Dr. Rosenthal has nothing to disclose.