TY -的T1 -视频眼球追踪跟进奥玛仕病人有别于控制(5350)JF -神经学乔-神经学六世- 94 - 15补充SP - 5350 AU - Kaajal Parbhoo盟——布莱恩j .白人非盟-唐纳德首页·c·布里恩盟埃菲Viguiliouk AU -道格拉斯·p·穆尼奥斯盟大肠安叶Y1 - 2020/04/14 UR - //www.ez-admanager.com/content/94/15_Supplement/5350.abstract N2 -目的:评估患者的眼球追踪之间的差异的历史斜视眼阵挛肌阵挛性共济失调综合征(奥玛仕)与健康对照组相比。背景:奥玛仕是一种罕见的免疫介导的神经紊乱,影响主要是导致婴幼儿长期行为和学习问题尽管解决其他神经系统症状。视频眼动跟踪是一种非侵入性的方法,其结果与其他人群的认知功能。规范化Scanpath凸起(NSS)成绩源于计算显著模型利用特征图渠道如亮度、闪烁、运动、脸和颜色。当一个新的视频开始,卓越成绩第一3跳阅已被证明是由自下而上加工而跳阅4 +驱动自上而下的加工。本横断式研究设计/方法:包括青年(n = 12、8 f、67个月,平均年龄iqr44 - 72)历史的奥玛仕和健康的年龄和性别匹配的控制(n = 12 8 f,平均年龄60.5个月iqr44 - 97)。标准化收集临床数据包括人口统计、临床、实验室和影像学结果。视频进行眼动跟踪使用Eyelink1000眼动跟踪(SR研究有限公司,渥太华,加拿大)。统计分析了使用JASP 0.11.1(版本)。结果:显著差异(p & lt;0.05)存在于意味着NSS奥玛仕病人之间的参数和控制,包括:闪烁NSS (1 - 3) (3.55 vs 4.26, p = 0.037),取向NSS (1 - 3) (2.36 vs 2.67, p = 0.044),红绿NSS (1 - 3) (3.2 vs 3.6, p = 0.043),自民党NSS) (4 +) (2.5 vs 3.0, p = 0.022),亮度NSS (4 +) (2.4 vs 2.8, p = 0.044),和脸NSS (4 +) (2.7 vs 3.9 p = 0.004)。结论:视频眼动跟踪奥玛仕病人有别于控制,特别是当看着自下而上和自上而下的显著措施建议关注和认知过程的差异。这可能心脏病临床表现在反应时间度量。 Future studies are needed to confirm these findings and investigate correlations between cognitive metrics and eye tracking results.Disclosure: Dr. Parbhoo has nothing to disclose. Dr. White has nothing to disclose. Dr. Brien has nothing to disclose. Dr. Viguiliouk has nothing to disclose. Dr. Munoz has nothing to disclose. Dr. Yeh has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Novartis speaker’s honorarium, Teva unrestricted funding for an educational symposium, Juno Therapeutics, Scientific Advisory Panel. ACI, relapse adjudication with the following funding sources: OIRM, MSSC/MSSF, NMSS, SickKids Foundation, CBMH, Guthy Jack. ER -