TY - T1的评估报告的可靠性病史老年人(2296)JF -神经学乔-神经学六世- 94 - 15补充SP - 2296 AU -格里高利天非盟-埃里森长盟约翰莫里斯Y1 - 2020/04/首页14 UR - //www.ez-admanager.com/content/94/15_Supplement/2296.abstract N2 -目的:确定病史在社区老年人的准确性。背景:一个可靠的历史是至关重要的,建立准确的临床诊断,优先调查和选择合适的治疗方法;然而,很少有研究严格评估的可靠性病史或影响可靠性的因素。设计/方法:participant-specific因素之间的关联和准确的报告中风和糖尿病是评估使用多变量逻辑回归对1401名参与者进行了纵向研究骑士阿尔茨海默病研究中心(圣路易斯,密苏里州),其中包括425名参与者痴呆(30.3%)。历史验证了一个可靠的间接源在所有参与者。中风和糖尿病被选为索引变量作为中风和hemoglobinA1c金本位观测大脑核磁共振(糖化血红蛋白),糖尿病通常获得的参与者。结果:25/862(2.9%)的参与者支持中风的历史,这是在8/25在MRI确诊(阳性预测值17.4%)。中风在38/837(4.5%)的MRI检测出那些没有报道中风(消极的预测价值,95.5%)。年龄(或每十年= 1.7,95% ci: 1.2—-2.5)和使用一个不相关的间接来源(或= 2.0,95% ci: 1.03—-3.7)与更大的可能性是不准确的报告。190/1322(14.4%)的参与者报告糖尿病史,在105/190确认与糖化血红蛋白(阳性预测值55.3%)。糖化血红蛋白≥6.5%中检测出29/1132(2.6%)的人否认糖尿病(消极的预测价值,97.4%)。非裔美国人(或= 1.6,95% ci: 1.02—-2.6)和高血压(或= 2.6,95%置信区间ci: 1.5 - -4.2)或糖化血红蛋白与葡萄糖耐量(或= 4.2,95% ci: 2.7—-6.4)报告的历史糖尿病的几率较高。 Cognitive impairment was not associated with inaccurate reporting.Conclusions: The accuracy of reported history of diabetes and stroke was low in older community-dwelling participants, independent of cognitive status. A history of diabetes or stroke should be objectively confirmed when relevant to decision making in clinical or research settings.Disclosure: Dr. Day has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with DynaMed%20(EBSCO%20Health), Parabon Nanolabs. Dr. Day holds stock and/or stock options in ANI Pharmaceuticals (a generic pharmaceutical company).Dr. Long has nothing to disclose. Dr. Morris has nothing to disclose. ER -