PT -期刊文章盟-格雷戈里天盟-埃里森长盟——约翰·莫里斯TI -评估的可靠性报告病史老年人(2296)DP - 2020年4月14日第六TA -神经病学PG - 2296 - 94 IP - 15补充4099 - //www.ez-admanager.com/content/94/15_Supplement/2296.short 4100 - ht首页tp://www.ez-admanager.com/content/94/15_Supplement/2296.full所以Neurology2020 4月14日;94 AB -目的:确定病史在社区老年人的准确性。背景:一个可靠的历史是至关重要的,建立准确的临床诊断,优先调查和选择合适的治疗方法;然而,很少有研究严格评估的可靠性病史或影响可靠性的因素。设计/方法:participant-specific因素之间的关联和准确的报告中风和糖尿病是评估使用多变量逻辑回归对1401名参与者进行了纵向研究骑士阿尔茨海默病研究中心(圣路易斯,密苏里州),其中包括425名参与者痴呆(30.3%)。历史验证了一个可靠的间接源在所有参与者。中风和糖尿病被选为索引变量作为中风和hemoglobinA1c金本位观测大脑核磁共振(糖化血红蛋白),糖尿病通常获得的参与者。结果:25/862(2.9%)的参与者支持中风的历史,这是在8/25在MRI确诊(阳性预测值17.4%)。中风在38/837(4.5%)的MRI检测出那些没有报道中风(消极的预测价值,95.5%)。年龄(或每十年= 1.7,95% ci: 1.2—-2.5)和使用一个不相关的间接来源(或= 2.0,95% ci: 1.03—-3.7)与更大的可能性是不准确的报告。190/1322(14.4%)的参与者报告糖尿病史,在105/190确认与糖化血红蛋白(阳性预测值55.3%)。 HbA1c ≥6.5% was detected in 29/1132 (2.6%) of those who denied diabetes (negative predictive value, 97.4%). African Americans (OR=1.6, 95%CI: 1.02–2.6) and those with hypertension (OR=2.6, 95%CI: 1.5–4.2) or HbA1c compatible with impaired glucose tolerance (OR=4.2, 95%CI: 2.7–6.4) had greater odds of reporting a history of diabetes. Cognitive impairment was not associated with inaccurate reporting.Conclusions: The accuracy of reported history of diabetes and stroke was low in older community-dwelling participants, independent of cognitive status. A history of diabetes or stroke should be objectively confirmed when relevant to decision making in clinical or research settings.Disclosure: Dr. Day has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with DynaMed%20(EBSCO%20Health), Parabon Nanolabs. Dr. Day holds stock and/or stock options in ANI Pharmaceuticals (a generic pharmaceutical company).Dr. Long has nothing to disclose. Dr. Morris has nothing to disclose.

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