RT期刊文章SR电子T1颅内大动脉动脉粥样硬化(1123)内小血管血管病变怀有摩根富林明神经学神经学乔FD Lippincott Williams &威尔金斯SP 1123签证官94 15补充A1托马斯·w·梁A1信义愣A1 Yannie秀A1文森特Ip A1苏首页马ho A1圣文德Ip A1西蒙于年2020 UL //www.ez-admanager.com/content/94/15_Supplement/1123.abstract AB目的:研究小血管血管病变的共处下属分支来自高档颅内大动脉atherosclerosisBackground:颅内动脉粥样硬化疾病(ICAD)是全球一个主要的缺血性中风亚型。了解中风机制ICAD和她对射孔器腔隙综合征的中风在支架可能通知治疗策略。设计/方法:急性缺血性中风患者归因于高档(60 - 99%)大脑中动脉(MCA)或基底动脉(BA)狭窄进行了三维旋转血管造影术(3半径标注)的开放描述下属分支发出立即从狭窄的部分。纹状体外动脉增MCA狭窄,我们审查,前颞动脉,和偶尔从早期M2分支水平段M1。对于英航病变,我们检查了小脑上动脉和前下小脑动脉。我们诊断分支动脉粥样硬化疾病(坏的管理者)如果一个开口病变动脉粥样化阻挡> 50%的孔下属分支/射孔器。坏可能是“相邻坏”如果交界动脉粥样化是连续的和形态学离不开父母的主要污染斑块;或“孤立的坏”如果orifical动脉粥样化离散从父斑块。我们内在的小血管血管病变诊断如果steno-occlusion独特的远端正常孔。结果:146例患者中窝藏MCA (n = 132)或BA斑块(n = 14),管腔狭窄中值为75%。101名患者(69%)有进一步steno-occlusions穿透动脉/下属分支机构在这些高档ICAD段。 By anatomic location, these small-vessel steno-occlusions (n=107) were primarily orifical (due to adjoining BAD (n=88) or isolated ostial atheroma (n=6)). Distal intrinsic vasculopathy was much less common (n=13).Conclusions: Concurrent small-vessel vasculopathy was frequent in ICAD, and the predominance of orifical obstructive atheroma accounted for common occurrence of lacunar syndrome in ICAD and the risk of perforator jailing or occlusion during stenting in this subgroup.Disclosure: Dr. Leung has nothing to disclose. Dr. Leng has nothing to disclose. Dr. Soo has nothing to disclose. Dr. Ip has nothing to disclose. Dr. Sze Ho has nothing to disclose. Dr. Ip has nothing to disclose. Dr. Yu has nothing to disclose.