PT -期刊文章盟Helaina主持人非盟-林Jung-Yi盟Churl-Su Kwon盟Parul Agarwal AU - Madhu Mazumdar盟娜塔莉Jette TI -痴呆的同现癫痫患者与30天重新接纳——以人群为基础的研究(2413)DP - 2021年4月13日TA -神经病学PG - 2413 VI - 96 IP - 15补充4099 - //www.ez-admanager.com/content/96/15_Supplement/2413.short 4100 - //www.ez-admanager.com/content/96/15_Su首页pplement/2413.full所以Neurology2021 4月13;96 AB -目的:确定癫痫患者痴呆在40岁与30天再次住院,住院死亡率,放电的性格和住院时间。背景:老年痴呆症和癫痫经常共现和与不良健康状况相关联,增加医疗利用率。的文献重新接纳之间的关系和同现痴呆和癫痫是不足。设计/方法:回顾性队列研究使用了2014年全国范围内再入院数据库,包含的数据来自全美医院放电和再入院。癫痫症和老年痴呆症被确定使用之前ICD-9-CM码进行验证。主要结果是30天重新接纳。其他结果重新接纳的原因,放电处理,住院死亡率和住院时间。多变量逻辑回归是用来检查癫痫的30天重新接纳和痴呆之间的联系。其他结果利用未经调整的多项物流相比,二项物流和线性回归。所有重量占调查,分析集群和地层。Results: Epilepsy patients with dementia (n=15,588) had longer hospital stays [15% (95%CI 10–20%)], and higher odds of readmission [OR 1.11 (95%CI 1.05–1.17)], transfer to another facility [OR 2.18 (95%CI 1.93–2.46)], and in-hospital mortality [OR 1.50 (95%CI 1.25–1.79)] compared to those without dementia (n=86,289). The top two causes of readmission were septicemia (dementia: 14.8%; no dementia: 9.4%) and epilepsy/convulsions (dementia: 5.9%; no dementia: 6.2%). Other top 10 causes of readmissions in those with epilepsy and dementia which were not present in those without dementia included delirium (5.2%), urinary tract infections (5.0%), and aspiration pneumonitis (4.3%).Conclusions: Dementia in epilepsy is associated with worse outcomes, including higher in-hospital mortality and higher readmissions. Potentially preventable causes of readmission in those with epilepsy and dementia were identified, including delirium, urinary tract infection and aspiration pneumonitis. Future studies are needed to inform interventions aimed at decreasing premature mortality and reducing potentially preventable readmissions in this vulnerable population.Disclosure: Dr. Lehrer has nothing to disclose. Jung-Yi Lin has nothing to disclose. Dr. Kwon has nothing to disclose. Parul Agarwal has nothing to disclose. Madhu Mazumdar has received personal compensation for serving as an employee of Icahn School of Medicine at Mount Sinai Hospital. Dr. Jette has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for ILAE Epilepsia. The institution of Dr. Jette has received research support from NIH. The institution of Dr. Jette has received research support from AES. The institution of Dr. Jette has received research support from PCORI.