TY - T1的中风危险因素的综合分析HIV在乌干达serostatus:影响中风的预防在撒哈拉以南的非洲(p1 - 1.虚拟)JF -神经学乔-神经学六世- 98 - 18补充SP - 3846 AU -阿米尔Mbonde AU -乔纳森·张盟Kisekka Musubire Adrian Kayanja AU -参孙Okello盟盟首页-摩西能盟-雅各布Nkwanga盟-安德鲁Katende AU -费利西亚Chow盟迪安娜塞勒AU - Cumara O 'Carroll盟马克Siedner Y1 - 2022/05/03 UR - //www.ez-admanager.com/content/98/18_Supplement/3846.abstract N2 -目的:确定缺血性中风和出血性中风的风险因素相差HIV serostatusBackground:中风的发病率正在上升在撒哈拉以南的非洲(SSA)和艾滋病毒感染被认为是一个关键的风险因素。然而,数据中风危险因素在抗逆转录病毒治疗(ART)的时代是稀疏的。设计/方法:我们进行了一项匹配的队列研究在乌干达在两个三级医院。我们参加艾滋病患者(PWH)呈现急性中风和匹配他们的性别和中风类型未感染艾滋病毒(HIV−)个人。我们收集的数据在中风危险因素和安装逻辑回归模型来评估如果缺血性中风和出血性中风的风险因素相差HIV serostatusResults:我们招收了262名参与者:105 PWH和157−HIV。艺术是5年时间中位数,CD4细胞计数中值为214细胞/ uL。在所有参与者与缺血性中风(n = 184)、高血压(53%)、心理社会应激(65%),低密度脂蛋白升高(51%)和糖尿病(22%)是很常见的。PWH与缺血性中风更有可能有高甘油三酯血症(优势比1.63;95%可信区间1.04,2.55,p = 0.03),报告饮酒(优势比2.84;95%可信区间1.32,6.14,p = 0.008)和抑郁(优势比5.64;95%可信区间1.32,24.02,p = 0.02)同时艾滋病−人更可能是年龄比; 55 years (AOR 0.43; 95%CI 0.20–0.95, p=0.037), have an irregular pulse rhythm (AOR 0.31; 95%CI 0.10–0.98, p=0.047) and report low fruit consumption (AOR 0.39; 95%CI 0.18–0.83, p=0.014). Among all participants with hemorrhagic stroke (n=78), hypertension (58%) and psychosocial stress (74%) were common, but we found no differences in the prevalence of risk factors between PWH and HIV−.Conclusions: PWH with ischemic stroke in Uganda present at a younger age, and with a combination of traditional and psychosocial risk factors. By contrast, HIV− persons more commonly present with arrhythmia. A differential approach to stroke prevention might be needed in these populations.Disclosure: Dr. Mbonde has nothing to disclose. Dr. Chang has nothing to disclose. Dr. Musubire has nothing to disclose. Samson Okello has nothing to disclose. Dr. Kayanja has nothing to disclose. Dr. Jacob has received personal compensation in the range of $500-$4,999 for serving as a Consultant for mbarara university. Dr. Katende has nothing to disclose. Dr. Chow has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Medicolegal consulting. The institution of Dr. Chow has received research support from NIH. Dr. O'Carroll has nothing to disclose. Mark Siedner has nothing to disclose. ER -