TY -的T1 -在常规临床脑电图异常报告与谵妄严重性(P2.230) JF -神经学乔-神经学六世- 88 - 16补充SP - P2.230盟Anudeepthi Neelagiri AU - Eyal泡菜盟Avinash首页 Sagi盟——m·布兰登·威斯多佛Y1 - 2017/04/18 UR - //www.ez-admanager.com/content/88/16_Supplement/P2.230.abstract N2 -目的:确定脑电图(EEG)特征之间的关系描述的常规临床报告和谵妄症状。背景:谵妄是一种急性疾病的关注和意识影响多达30%的住院病人,尤其是老年人。谵妄患者的风险增加,死亡率和长期的认知障碍。而精神错乱是越来越多的研究和临床实践中定义使用行为尺度,没有验证生物标志物谵妄的严重性。我们确定常规脑电图异常之间的关系和精神错乱的严重程度。设计/方法:我们正在进行一项前瞻性研究的成人,non-intubated住院住院患者进行脑电图改变精神状态的评价。痴呆患者在基线被排除在外。每个病人对谵妄评估在1小时内使用混乱的脑电图评估方法(CAM),包括使用CAM-S谵妄严重程度评分。标准临床脑电图报告综述了确定各种特性的存在与否主要包括后节奏,θ/δ放缓,三相的波。患者按每个分组可能CAM-S严重程度评分(0 /影响- 19 /严重的精神错乱)。结果:数据来自190名患者已经聚集到目前为止平均年龄为58.8岁(标准差18.4); 42.1% were female. 53.7% of patients were delirious according to CAM criteria. The EEG feature most sensitive for delirium was the presence of either theta or delta slowing (92.2% sensitive, 56.8% specific). Delirium severity as measured by the CAM-S was strongly correlated with the likelihood of either theta or delta slowing on the EEG (Spearman R = 0.837, p < 0.001).Conclusions: Abnormalities identified by routine clinical EEGs, in particular theta or delta slowing, show strong and systematic correlations with the severity of delirium. Quantitative analysis may further improve the diagnostic specificity of EEG for delirium.Study Supported by:Dr. Kimchi has received support from the American Brain Foundation Clinical Research Training Fellowship and the NIH-NIA. Dr. Westover has received research support from NIH-NINDS.Disclosure: Dr. Neelagiri has nothing to disclose. Dr. Kimchi has nothing to disclose. Dr. Sagi has nothing to disclose. Dr. Westover has nothing to disclose. ER -