PT -期刊文章盟-雪莉Fung盟瑞秋肯尼AU -萨拉·海曼盟-阿齐兹Seixas AU - Girardin jean - louis AU -劳拉Balcer盟Sujata Thawani TI -失眠,严重后遗症的COVID-19门诊神经病学组(p1 - 13.005) - 10.1212 / WNL援助。首页0000000000204325 DP - 2023年4月25日TA -神经病首页学第六PG - 4946 - 100 IP - 17补充2 4099 - //www.ez-admanager.com/content/100/17_Supplement_2/4946.short 4100 - //www.ez-admanager.com/content/100/17_Supplement_2/4946.full所以Neurology2023 4月25日;100 AB -目的:本研究旨在评估水平的一群PASC患者的失眠。背景:失眠患者可能是一个症状,急性COVID-19后遗症(PASC)经验。设计/方法:本研究分析了93年的症状SARS-CoV-2积极招募从门诊病人神经诊所。首页在最初的基线评估和1-year-follow起来,使用标准化的评估尺度在一次电话面试。失眠严重程度指数是一个验证的工具来评估失眠症状。在完成了后续的42例,症状之间的初始和1年随访评价比较。结果:基线,51%的参与者表示他们有睡眠困难,而在随访为48%。后续的参与者中,47%没有临床意义上的失眠,33%报道阈下失眠,16%报告中度临床失眠,5%报道严重临床失眠。的人失眠(n = 20)报道,11(55%)没有失眠或阈下失眠,和9在中度到重度的范围规模三军情报局。失眠在基线评估与ISI分数无关的后续访问。 Binary ISI (scores less than 15 = no or subthreshold insomnia or greater than 15=moderate to severe insomnia) was associated with Neuro-QOL anxiety t-score (p=0.034, logistic regression adjusting for age, gender, race/ethnicity), fatigue t-score (p=0.009), depression t-score (p=0.023) and MOCA score (p=0.048). Binary ISI was not associated with HIT6 or number of headaches in the last 30 days on the AMPP questionnaire.Conclusions: Sleep disturbances may be an important symptom which may be overlooked in patients suffering from PASC, which can be ongoing and disruptive for periods of years. Furthermore, association with worsened quality-of-life measures for depression, fatigue, and anxiety make this area of PASC one that warrants further attention.Disclosure: Ms. Fung has nothing to disclose. Rachel Kenney has nothing to disclose. Ms. Hyman has nothing to disclose. Azizi Seixas has nothing to disclose. Girardin Jean-Louis has nothing to disclose. An immediate family member of Dr. Balcer has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Children’s Hospital of Philadelphia. Dr. Balcer has received personal compensation in the range of $50,000-$99,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for North American Neuro-Ophthalmology Society. Dr. Thawani has nothing to disclose.