@article {Deuschl1432作者= {Guenther Deuschl和Griet罗兰转发诺伯特·科瓦奇和弗雷德里克克莱门特公关舒尔曼},title ={震颤减少使用DBS:一个真实的结果,前瞻性多中心特发性震颤注册(p7 - 11.004)},体积={100},数量={17补充2},elocation-id = {1432} = {2023}, doi = {10.1212 / WNL。出版商0000000000201927}= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:评估结果具有多个独立的定向DBS系统电流控制(MICC)技术在特发性震颤首页患者植入(ET)的护理标准。背景:等是最常见的神经系统疾病之一,影响约0.9 \ %的世界人口。医疗专注于运动症状,管理和治疗选择包括药物治疗、腹侧中间核(Vim)丘脑切开术,和/或丘脑脑深部电刺激(DBS)。目前,Vim DBS推荐作为治疗选择合适的科目与ET (Zesiewicz Wharen 2017年,2005)。设计/方法:在这个前瞻性,标签上,多中心,国际DBS注册,登记患者植入定向MICC-based DBS系统(Vercise,波士顿科学)。病人随访3年,整体生活质量改善及评估等症状。不良事件也被收集。结果:迄今为止,30例植入(= 64.8 {\ textpm} 15.1岁意味着(SD), 53.1 \ %男性)意味着疾病持续时间为19.3年。17.3分的变化探索总结指数在12个月内代表指出临床显著差异(\ > 4.47分变化)(品特2019)。此外,平均9小时地震减少在一个典型的一天是指出在基线(14.7小时和6.5小时在12个月)。此外,基于FTMTRS的严重性规模,当比较残疾在12个月(与基线),没有病人报告经历明显的残疾在基线(vs . 9.4 \ %), 16.7 \ %报道中度残疾在基线(vs . 81.3 \ %)和83.3 \ %报道轻度残疾在基线(9.4 vs \ %)。结论:初步结果从这个正在进行的注册表显示的生活质量,临床上重要成果以及运动机能,从而反映整体改善残疾患者(即。,残疾的概要文件从中度/重度更轻/中度残疾)。 This registry represents the first comprehensive, large-scale collection of real-world outcomes with MICC-based DBS systems for ET.Disclosure: Dr. Deuschl has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Boston Scientific Cavion Functional Neuromodulation. The institution of Dr. Deuschl has received research support from Medtronic. Dr. Deuschl has received publishing royalties from a publication relating to health care. Dr. Loret has nothing to disclose. The institution of Norbert Kovacs has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbvie. The institution of Norbert Kovacs has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Abbott. The institution of Norbert Kovacs has received personal compensation in the range of $500-$4,999 for serving as a Consultant for boston Scientific. Norbert Kovacs has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Abbvie. Norbert Kovacs has received personal compensation in the range of $500-$4,999 for serving as an officer or member of the Board of Directors for Hungarian Scientific Parkinson{\textquoteright}s Disease Society. The institution of Norbert Kovacs has received research support from Abbott. The institution of Norbert Kovacs has received research support from Hungarian National Research Board. Dr. Clement has nothing to disclose. P.R. Schuurman has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Boston Scientific. P.R. Schuurman has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medtronic.}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/100/17_Supplement_2/1432}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }