PT -期刊文章盟Vasundhra马亨德拉AU -亚历山德拉Parashos Ezequiel Gleichgerrcht TI - AU -马克·瓦格纳盟的创伤性脑损伤后获得Speech-to-Color联觉。(p4 - 12.002) - 10.1212 / WNL援助。0000000000204108 DP - 2023年4月25日TA -神经病首页学第六PG - 4616 - 100 IP - 17补充2 4099 - //www.ez-admanager.com/content/100/17_Supplement_2/4616.short 4100 - //www.ez-admanager.com/content/100/17_Supplement_2/4616.full所以Neurology2023 4月25日;100 AB -目的:NABackground:联觉是一个独特的主观现象一个感觉形态抒发感性经验的感觉形态无关。Chromesthesia是一种特定的sound-to-color的联觉,没有颜色信息的听觉刺激诱发的颜色感知。关于联觉神经生物学的知识是有限的,构成对其检测和管理的挑战,从而创建一个需要更多lesion-symptom探索。设计/方法:我们报告一个71岁的原本健康的左撇子女性开发联觉与后续holocephalic遭受创伤性脑损伤后硬膜下出血需要颅骨切开术。这门课是由焦癫痫持续状态复杂成像显示皮质水肿。出院后不久,病人症状的报道看到的颜色投射在口语从人们的口中,chromesthesia的暗示。颜色生动在强度出现但会迅速消散成蒸汽的外观。 During neuropsychological testing, patient described that specific colors were associated with different words and were repeatable. For example, the word “the” was associated with color blue. Interestingly, her symptoms were specific to expressive language and not reproducible with music, singing or other non-verbal sounds such as dogs barking. Viewing videos of people speaking would trigger color but not if the videos contained music, singing or other non-verbal sounds. Patient reported listening to music as a therapeutic intervention when surrounded by multiple conversations in a crowded environment.Results: The case shows acquired chromesthesia presenting with word-specific color changes induced solely by oral speech elicited by others and not by other non-verbal sounds, including music.Conclusions: We report the first case of acquired human oral speech-to-color synesthesia following Traumatic Brain Injury. Acquired forms of synesthesia tend to result from drug intoxication or neurological disorders, including injury. We discuss our patient’s acquired form of chromesthesia in the context of multiple theories associated with multimodal integration in the adult brain.Disclosure: Dr. Mahendra has nothing to disclose. Dr. Parashos has nothing to disclose. Dr. Wagner has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for Insurance. Dr. Gleichgerrcht has nothing to disclose.