RT期刊文章SR电子T1 GUILLLAIN-BARRE综合症相关ZIKA病毒感染在巴西(P5.119)摩根富林明神经病学神经学乔FD Lippincott Williams &威尔金斯SP P5.119 VO 88是16补充A1首页 Amilton安图内斯Barreira A1威尔逊品牌,Jr . A1 Alexandre Marreco A1卡米拉·德·阿基诺克鲁兹A1凡妮莎品牌A1达尼洛卢卡斯阿尔维斯Sposito A1 Taline蒙泰罗克莱因A1巴特·雅各布斯A1 Benedito安东尼奥·洛佩斯丰A1 IGOS-ZIKA研究小组2017年UL //www.ez-admanager.com/content/88/16_Supplement/P5.119.abstract AB目的:我们报告的临床、电生理学和实验的方面Gillain-Barre综合征与ZIKA病毒(GBS-ZIKV)评估在小溪Preto,东南部城市在圣保罗州,巴西,从2016年1月至5月。背景:GBS发病率增加在ZIKV的暴发。设计/方法:GBS和米勒费雪症候群(MFS)和变异是根据建议国际GBS的诊断结果研究Zika病毒(IGOS-ZIKA)。患者连环神经系统检查和nc,和样本的血液,尿液,和CSF登革热病毒(DENV)和ZIKV抗体,和rt - pcr (CDC)方法得到治疗开始前。结果:包括17例GBS患者和11例(65%)有ZIKV积极PCR对DENV不利。从2到4 GBS残疾分数不同。9名患者使用血浆置换治疗与免疫球蛋白和两个。从四个病人随访三个或更多个月,只有一个没有恢复行走能力。所有患者脑脊液正常或hyperproteinorachia,,只有一个除外。罕见GBS变体:1)双边、和不对称的面瘫,脸部和手指myoquimias,远端感觉异常和轴向小脑综合症(CAS)。2)中科院、VI脑神经双边麻痹性痴呆,嗜睡,后减少腿部运动强度近端,第一周的CSF有脑脊液细胞增多(95细胞),和hyperproteinorachia(84毫克/ cl)在第四周(一个重叠综合征,Bickerstaff脑炎+ MFS + GBS)。主要是轴突发生模式,但四脱髓鞘EMG注册。Conclusions: The GBS incidence was two times higher when compared with the last three years incidence. A definitive GBS-ZIKV requires the analysis of serum, urine, and CSF samples. In conclusion, Zika virus infection may be followed by a spectrum of different GBS subtypes in Brazil, including various clinical and electrophysiological variants.Study Supported by: FAEPA. Fundação deApoio ao Ensino, Pesquisa eAssistência do Hospital das Clínicas daFaculdade de Medicina de RibeirãoPreto da Universidade deSãoPauloDisclosure: Dr. Barreira has received personal compensation for activities with Baxter as a speaker and participant in an advisory board. Dr. Marques has received personal compensation for activities with Baxter as a speaker and/or advisory board member. Dr. Marreco has nothing to disclose. Dr. Cruz has nothing to disclose. Dr. Marques has nothing to disclose. Dr. Sposito has nothing to disclose. Dr. Klein has nothing to disclose. Dr. Jacobs has nothing to disclose. Dr. Fonseca has nothing to disclose. Dr. study group has nothing to disclose.