@article {MarkvardsenP4.142作者= {Lars H {\ o} j Markvardsen和克里斯蒂安Overgaard和卡伦Heje和S {\ o}任正非Sindrup, Ingelise克里斯琴森和约翰vis和亨宁安徒生},title ={交替阻力和耐力训练可以提高肌肉力量和有氧能力患者的慢性炎性脱髓鞘多神经病(P4.142)},体积={88}={16}补充数量,elocation-id = {P4.142} ={2017},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={摘要目的:探讨有氧和抵抗运动的影响患者的慢性炎性脱髓鞘多神经病(CIDP)。首页背景:有氧运动和阻力运动导致更高的有氧能力和各种神经肌肉疾病患者的肌肉力量。然而,稀疏描述是否患有慢性炎性脱髓鞘多神经病(CIDP)从锻炼中受益。设计/方法:在这个控制研究中,十八CIDP患者皮下免疫球蛋白被分配到12周的有氧运动之后,12周的抵抗运动,反之亦然。锻炼之前,所有病人的试车期12周没有任何预定的运动。有氧运动每周至少三次上执行一个测力计的自行车在70 \ %的强度最大心率。抵抗运动每周进行三次单边训练的膝盖和肘部弯曲/扩展与常规负荷的增加。主要结果有氧能力(氧气摄入量)和最大等速肌力的膝盖和肘部弯曲/扩展。生活质量(QoL)和疲劳是次要参数。结果:13例完成会话和四个完成有氧(n = 2)或阻力训练时期(n = 2)。在试车期间,氧气摄入量和肌肉力量改变(26 {\ textpm} 6 vs . 26 {\ textpm} *最低为1 * 6毫升公斤(p = 0.80)和245 {\ textpm} 83和246 {\ textpm} 85海里(p = 0.17)。 Following aerobic exercise, VO2-max increased by 11\%, (27{\textpm}7 to 30{\textpm}7 ml*min-1*kg-1 (p=0.02)). Resistance exercise resulted in a 14\% increase in combined muscle strength of upper and lower extremities (243{\textpm}77 to 276{\textpm}91 Nm (p=0.0004)). QoL and fatigue were unchanged.Conclusions: Aerobic and resistance exercise training are safe and improve fitness and strength in CIDP patients treated with immunoglobulin.Study Supported by:Sponsored by Octapharma PharmaceuticalsDisclosure: Dr. Markvardsen has received personal compensation for activities with Octapharma Pharmaceuticals as a speaker. Dr. Markvardsen has received research support from Octapharma Pharmaceuticals. Dr. Overgaard has nothing to disclose. Dr. Heje has nothing to disclose. Dr. Sindrup has nothing to disclose. Dr. Christiansen has nothing to disclose. Dr. Vissing has received personal compensation for activities with Alexion Pharmaceuticals and Ultragenyx as an advisory board member. Dr. Andersen has nothing to disclose.}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/88/16_Supplement/P4.142}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }