@article {ZalewskiP5.251作者={尼古拉斯Zalewski雨果·博塔和珍妮弗Whitwell Val劳和丹尼斯·迪克森和基思·约瑟夫},title ={正病理证实4 r-tauopathy变体(P5.251)},体积={82}={10}补充数量,elocation-id = {P5.251} ={2014},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={目的:我们研究病理确诊病例4 r-tauopathies来确定不同的摄影模式比先前描述的代谢减退存在。首页背景:临床4 r-tauopathies可以异构和难以诊断。代谢减退的摄影模式已经在临床上怀疑之前报道4 r-tauopathies。考虑到病理确认没有被用作入选标准然而,在这些研究可能存在非典型病例被排除在外。设计/方法:我们确定解剖证实4 r-tauopathies摄影成像表现在2010 - 2013的进行性核上的麻痹(PSP)成像研究。临床特征和摄影成像比较一组正常控制。结果:9例,其中7解剖证实PSP,被确定。我们还发现了两例球状胶质tauopathy (GGT)。主要影像学表现包括双边尾代谢减退在8例,轻度不对称在七丘脑代谢减退,在补充运动区和双边代谢减退6。没有观察到的差异在PSP和GGT之间。 CONCLUSIONS: As previously described, 4R-tauopathies are associated with frontal, caudate, and thalamic hypometabolism on FDG-PET. This is the first report of FDG-PET in GGT and although our series was limited to two cases, there was no evidence of differentiating FDG-PET features to distinguish GGT from PSP.Disclosure: Dr. Zalewski has nothing to disclose. Dr. Botha has nothing to disclose. Dr. Whitwell has nothing to disclose. Dr. Lowe has received personal compensation for activities with Bayer Pharmaceuticals Corp. Dr. Lowe has received research support from GE Health Care, Siemens Molecular Imaging, and AVID Radiopharmaceuticals, Inc. Dr. Dickson has received personal compensation for activities with Neotope, Inc. as a consultant. Dr. Josephs has nothing to disclose.Wednesday, April 30 2014, 3:00 pm-6:30 pm}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/82/10_Supplement/P5.251}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }